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All Journal Klinikal Sains (Jurnal Analis Kesehatan)
Roza Liana Sukma
Universitas Abdurrab
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology

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EVALUASI DAN UJI AKTIFITAS ANTIOKSIDAN KRIM SEDIANAN DARI DAUN NANGKA (Artocarpus heterophyllus Lam.) MENGGUNAKAN METODE DPPH Sri Kartini; Roza Liana Sukma
Klinikal Sains : Jurnal Analis Kesehatan Vol. 14 No. 1 (2026): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v14i1.8085

Abstract

Jackfruit leaves (Artocarpus heterophyllus Lam.) are rich in bioactive compounds, including flavonoids, phenolics, tannins, and saponins, which exhibit antibacterial and antioxidant activities. These properties suggest their potential application as natural ingredients in anti-acne formulations. This study aimed to formulate an anti-acne cream containing ethanol extract of jackfruit leaves and to evaluate its physicochemical characteristics, including organoleptic properties, homogeneity, pH, and spreadability, as well as its antioxidant activity using the DPPH assay.The jackfruit leaf extract was obtained through maceration using 96% ethanol and incorporated into cream formulations at different concentrations (F0, F1, F2, and F3). The evaluation results demonstrated that all formulations possessed acceptable organoleptic characteristics, showed good homogeneity, maintained pH values within the skin-friendly range (4.5–6.5), and exhibited suitable spreadability values ranging from 5 to 7 cm. Antioxidant activity assessment revealed concentration-dependent effects, as indicated by the IC₅₀ values Formulations F0 (483.23 ppm and F1 (373.12 ppm) exhibited weak antioxidant activity, F2(156 .03 ppm)
Co-Authors Sri Kartini