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All Journal Healthcare Nursing Journal Journal of Microbiology, Biotechnology and Conservation
Hasan Ali Alsailawi
Department of Basic Sciences, Faculty of Dentistry, University of Kerbala, Karbala, 56001, Iraq
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Immunology & microbiology Nursing

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Evaluation of Hematological Alterations Associated with Arthritis among Individuals in Karbala City Hasan Ali Alsailawi
Journal of Microbiology, Biotechnology and Conservation Vol. 2 No. 1 (2026): Journal of Microbiology, Biotechnology and Conservation (jMBC)
Publisher : Master’s Program in Biology, Faculty of Mathematics and Natural Sciences, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/wd2e8208

Abstract

Arthritis can cause measurable hematological changes (anemia, leukocyte and platelet alterations, raised acute-phase markers). The current study aimed to evaluate hematological alterations among individuals diagnosed with arthritis in Karbala City and to compare these parameters with age- and sex-matched controls. Cross-sectional study enrolling adults (≥25 years) with clinical diagnosis of arthritis presenting to rheumatology/orthopedic clinics in Karbala Imam Hussein Medical City, Karbala Teaching Hospital for Children, and some health centers and private laboratories in Karbala Governorate during the period from December 20, 2022 to April 10, 2023, where (20). Controls: healthy volunteers matched by age and sex. Hematological tests: complete blood count (CBC) with indices, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and when available rheumatoid factor (RF) and anti-CCP. Demographics, clinical features, disease duration, and medication history collected. Primary outcomes: prevalence of anemia, leukocytosis/leukopenia, thrombocytosis/thrombocytopenia, and correlations with ESR/CRP. Statistical tests: t-test / Mann-Whitney U, chi-square, Pearson/Spearman correlation, multivariable linear/logistic regression. Significance p<0.05. (placeholder-insert observed frequencies, means, and key p-values.) (placeholder-summarise main hematological alterations found and clinical implications for diagnosis/management in Karbala.)
Renal and Metabolic Biomarker Alterations in Women with Breast Cancer: A Case–Control Study from Karbala, Iraq Hasan Ali Alsailawi
HealthCare Nursing Journal Vol. 8 No. 1 (2026): HealthCare Nursing Journal
Publisher : LP3M Universitas Muhammadiyah Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35568/healthcare.v8i1.7769

Abstract

Kidney dysfunction has gained increasing clinical importance as a comorbidity in patients with malignant disease, especially those suffering from solid tumors like breast cancer. The present work was designed to assess renal and metabolic biomarker dysregulations among women patients diagnosed with breast cancer compared with healthy subjects of Karbala city/Iraq. A hospital-based case–control study was performed from December 2018 to March 2019 in the Oncology Center of the Maternity and Children’s Hospital, Karbala. Seventy breast cancer women diagnosed with proven histology and 30 normal age-and sex-matched controls were included. Standardized biochemical assays were used to estimate concentrations of urea, creatinine, uric acid, glucose and total cholesterol in the serum. Data were analyzed statistically using the suitable parametric tests and significance was assumed as p < 0.05. The serum levels of urea, glucose and total cholesterol in breast cancer patients were significantly higher than those in normal controls (p < 0.05). On the other hand, serum creatinine and uric acid levels were lower in patients (p < 0.05). 45–55 years were the most affected group, accounting for the largest number of diagnosed patients. Breast cancer is characterized by marked perturbations in renal and metabolic biomarkers indicating subclinical renal damage and systemic metabolic irregularities. Regular follow-up monitoring of the kidney function-related variables should become part of breast cancer management to minimize renal effects and enhance therapeutic benefits.
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