Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Journal of Advanced Multidisciplinary Research
Jorgy Rahmat Syahhada
Medical Faculty, Unissula
Religion Aerospace Engineering Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Earth & Planetary Sciences Environmental Science Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mechanical Engineering Nursing Public Health Social Sciences

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Comparative In Vitro Antifungal Activity of 0.2% Chlorhexidine and 1% Povidone-Iodine Oral Antiseptic Solutions Against Candida albicans Jorgy Rahmat Syahhada
Journal of Advanced Multidisciplinary Research Vol 7, No 1 (2026): Vol 7 No 1 (2026)
Publisher : Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/jamr.7.1.1-10

Abstract

Alterations in the oral microbiota of Intensive Care Unit (ICU) patients, particularly those receiving mechanical ventilation, may increase the risk of Candida albicans colonization. Oral antiseptics such as chlorhexidine gluconate and povidone-iodine are commonly used; however, evidence regarding their antifungal efficacy remains limited. This study aimed to compare the in vitro antifungal efficacy of 0.2% chlorhexidine gluconate and 1% povidone-iodine against Candida albicans.This laboratory experimental study used a post-test-only control group design. Antifungal activity was evaluated using the Kirby–Bauer disk diffusion method on a standardized Candida albicans suspension (0.5 McFarland; 1×10⁸ CFU/mL). Inhibition zone diameters were measured after 24 hours of incubation at 37°C. Isolates were identified using standard microbiological methods and MALDI-TOF MS. Data were analyzed using the Mann–Whitney test after non-normality was confirmed by the Shapiro–Wilk test.The results showed that 0.2% chlorhexidine gluconate produced a median inhibition zone diameter of 20 mm (19–20 mm), which was significantly greater than that of 1% povidone-iodine (11 mm [10–11 mm]). The difference between the two treatment groups was statistically significant (p < 0.001).In conclusion, 0.2% chlorhexidine gluconate was more effective than 1% povidone-iodine in inhibiting the growth of Candida albicans in vitro.
Co-Authors