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Mariam Ulfah
Program Studi Sarjana Farmasi Fakultas Farmasi Universitas Muhammadiyah Ahmad Dahlan Cirebon
Biochemistry, Genetics & Molecular Biology Health Professions Nursing Public Health

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A AKTIVITAS FRAKSI DAUN PEPAYA JEPANG (Cnidoscolus aconitifolius) TERHADAP BAKTERI Staphylococcus aureus DAN JAMUR Trichophyton rubrum Ade Irawan; Mariam Ulfah; Ismanurrahman Hadi; Saddam Fadhillah N
Kieraha Medical Journal Vol 8 No 1 (2026): KIERAHA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran, Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/kmj.v8i1.12243

Abstract

A problem that occurs in most developing country such as Indonesia, is the many diseases caused by infections. Japanese papaya plants (Cnidoscolus aconitifolius) contain compounds which are considered to have potential as antimicrobial agents for treating infections. Antifungal and Antibacterial are compounds that can inhibit and kill the growth of fungi and bacteria, thereby preventing infection. This study used fractions from Japanese papaya leaf (Cnidoscolus aconitifolius) that had undergone a compound isolation process using the maceration method using 96% ethanol solvent, namely the n-hexane fraction, ethyl acetate fraction and butanol fraction. The results of the study showed that the most effective fraction in inhibiting the growth of Staphylococcus aureus bacteria was the butanol fraction with a concentration of 7.5%. The most effective fraction in inhibiting the growth of Tricophyton rubrum fungus was the ethyl acetate fraction with a concentration of 7.5%. Keywords : Papaya Japanese (Cnidoscolus aconitifolius), Staphylococcus aureus, Trichophyton rubrum.
Co-Authors Ade Irawan Ismanurrahman Hadi Saddam Fadhillah N