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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
I Gusti Ayu Widianti
Departemen Anatomi Fakultas Kedokteran Universitas Udayana Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Flavonoid dalam Pencegahan Gagal Ginjal Akibat Stres Oksidatif Muhammad Ashhabul Kahfi Mathar; Ni Made Linawati; Ida Ayu Ika Wahyuniari; I Gusti Ayu Widianti
Majalah Kedokteran Indonesia Vol 76 No 1 (2026): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.76.1-2026-1726

Abstract

Kidney failure is a growing global health problem, encompassing acute kidney injury and chronic kidney disease (CKD). CKD is a global health problem, and increased reactive oxygen species (ROS) play a major role in the pathogenesis of CKD through kidney inflammation and fibrosis.1 Recent epidemiological studies have linked flavonoid-rich diets to the incidence of kidney disease.2 Flavonoids are plant-derived phenylchroman compounds that comprise various subclasses, such as flavones, flavanols, isoflavones, anthocyanins, flavon-3-ols, and flavanones. Flavonoids are the third largest group of natural compounds after terpenoids and alkaloids and play a role in protecting the body from oxidative stress and inflammation.3 Phenolic compounds such as phenolic acids, flavonoids, and proanthocyanidins are abundant in plants as a defense mechanism against biotic and abiotic stress. Consumption of polyphenol-rich foods, such as fruits, vegetables, grains, spices, and herbs, is known to reduce the risk of various chronic and degenerative diseases associated with oxidative stress.4
Co-Authors Ida Ayu Ika Wahyuniari Muhammad Ashhabul Kahfi Mathar Ni Made Linawati