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Pra Panca Bayu Chandra
Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA

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PENGARUH VARIASI LAMA WAKTU PEREBUSAN BUNGA TELANG (Clitoria ternatea L.) TERHADAP KANDUNGAN ALKALOID DENGAN METODE SPEKTROFOTOMETRI UV-Vis Muhamad Yoga Firmansyah; Alip Desi Suyono Saputri; Rizka Wahyu Syahputra; Pra Panca Bayu Chandra
Jurnal Farmasi IKIFA Vol. 5 No. 2 (2026): JURNAL FARMASI IKIFA VOL. 5 NO. 2 JULI TAHUN 2026
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Butterfly pea flower (Clitoria ternatea L.) contains various secondary metabolites, including alkaloids. Boiling is commonly used by the community to prepare butterfly pea flower, but boiling duration may affect the level of active compounds extracted. This study aimed to determine the effect of boiling time variation on the alkaloid content of butterfly pea flower decoction and to identify the optimal boiling time. An experimental method was conducted using boiling times of 10, 20, and 30 minutes. Qualitative alkaloid identification was performed using Mayer, Wagner, and Dragendorff reagents, while total alkaloid content was determined by UV-Vis spectrophotometry using bromocresol green (BCG) as a complex-forming reagent. The results showed that all samples tested positive for alkaloids. The average alkaloid contents at boiling times of 10, 20, and 30 minutes were 0.1548, 0.2046, and 0.2917 mg CE/mL, respectively. Statistical analysis indicated a significant difference among treatments (p<0.05). The 30-minute boiling treatment produced the highest alkaloid content and was considered the optimum boiling time.
AKTIVITAS FOTOPROTEKTIF IN VITRO SEDIAAN KRIM EKSTRAK HERBA PUTRI MALU (Mimosa pudica L.) SEBAGAI TABIR SURYA In Rahmi Fatria Fajar; Dewi Rahma Fitri; Yulis Adriana; Handawati Silitonga; Pra Panca Bayu Chandra
Jurnal Farmasi IKIFA Vol. 5 No. 2 (2026): JURNAL FARMASI IKIFA VOL. 5 NO. 2 JULI TAHUN 2026
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

The sensitive plant (Mimosa pudica L.) has great potential as a raw material for cosmetics due to its bioactive compounds that can neutralize free radicals. One of its applications is as a sunscreen agent that protects the skin from the harmful effects of the sun’s ultraviolet (UV) radiation. This study aims to determine the Sun Protection Factor (SPF) value of a 70% ethanol extract of the sensitive plant, formulate it into a cream, and evaluate the physical characteristics and sunscreen activity of the formulation. The in vitro SPF value was calculated using UV-Vis spectrophotometry based on the Mansur formula. The cream formulations were prepared in four variations with different extract concentrations: F0 (0%), F1 (0.3%), F2 (0.6%), and F3 (0.9%). Physical evaluation of the formulations included organoleptic testing, homogeneity, spreadability, pH, and viscosity. The results of the physical evaluation showed that all four formulations exhibited good homogeneity. The spreadability test yielded results that met the requirements (5–7 cm), and the pH test results fell within the safe range for the skin (4.5–6.5). The viscosity of the creams decreased as the concentration of the added extract increased. The SPF test results for the cream formulations showed the following values: F0 at 1.8810 (no protection), F1 at 14.2306 (maximum protection category), F2 at 27.2598 (ultra protection category), and F3 at 33.1475 (ultra protection category). Conclusion: A 70% ethanol extract of the putri malu herb was successfully formulated into a sunscreen cream that meets physical quality requirements, and increasing the extract concentration significantly enhanced its photoprotective activity, reaching the ultra protection category.