Fariani Syahrul
Department of Epidemiology, Biostatistics, Population Studies and Health Promotion, Faculty of Public Health, Universitas Airlangga, Surabaya 60115, East Java, Indonesia

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Climate Variability and Dengue Dynamics: A Path Analysis in Surabaya, Indonesia Khuliyah Candraning Diyanah; Ririh Yudhastuti; Lilis Sulistyorini; Mahmudah; Heny Arwati; Hari Basuki Notobroto; Rahmat Dapari; Fariani Syahrul; Muhammad Rasyid Ridha; Babucarr Jassey; Aditya Sukma Pawitra; Diva Alishya Shafwah; Nafi’atul Irbah
JURNAL KESEHATAN LINGKUNGAN Vol. 18 No. 3 (2026): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v18i3.2026.275-285

Abstract

Introduction: Dengue fever is a climate-sensitive vector-borne disease. While many studies have documented associations between climate variables and dengue incidence, most rely on conventional regression approaches that fail to separate direct and indirect climatic pathways, limiting mechanistic understanding and utility for environmental health. This study aims to elucidate the interconnected effects of climatic variability on dengue incidence in Surabaya. This study integrates seasonal time-series decomposition and path analysis to distinguish direct and indirect climatic pathways, sunlight duration and wind speed. Methods: A retrospective ecological design, monthly dengue incidence data from 2020 to 2024 were integrated with meteorological variables, including rainfall, temperature, humidity, sunlight duration, and wind speed. Seasonal time-series decomposition was applied to characterize temporal dynamics, followed by path analysis within a structural equation modeling framework to quantify direct and indirect climatic effects. Results and Discussion: A pronounced seasonal pattern in dengue incidence, with peaks during the rainy season. Maximum temperature, relative humidity, sunlight duration, and minimum wind speed exerted significant direct effects on dengue incidence (p < 0.05). Rainfall showed no direct association but acted as a key upstream driver influencing other climatic variables. The structural model explained 52.1% of the variance in dengue incidence, highlighting the contribution of interconnected climatic processes. Conclusion: These findings demonstrate that dengue dynamics in tropical metropolitan environments are governed by complex climate-mediated pathways rather than isolated climatic predictors. This study novel environmental epidemiological evidence to support climate-informed dengue early warning systems and adaptive vector control strategies under climate variability and urban environmental change.
Effects of Clarias, Soy Protein, Moringa with Vitamin D Biscuit and Anti-TB Drugs on Blood Serum and Biochemical Profile of Tuberculosis-infected Rats Fariani Syahrul; Annis Catur Adi; Wizara Salisa; Noni Angelina Tazky Aulia; Livia Bellatrix Roberts; Muhammad Atoillah Isfandiari
Media Gizi Indonesia Vol. 21 No. 3 (2026): MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v21i3.439-452

Abstract

The surge of tuberculosis (TB) in Indonesia, reaching over 385 cases per 100,000 population in 2024, presents an evident public health challenge. Primary drug-based (OAT/anti-TB drugs) therapy has adverse effects, affecting patient compliance and health outcomes. Nutritional therapy derived from animal-plant protein enriched with vitamin D has been offered as an adjunct therapy. This study investigated the effectiveness of catfish-derived biscuit substitutes, isolated soy protein, and moringa flour enriched with vitamin D in improving physical and immunological outcomes. Using a completely randomized design, the research process encompassed product development and pre-clinical testing in 35 adult white male Rattus norvegicus aged 8 weeks weighing 130-140 grams which were randomly divided into five groups, namely negative control (K0), Mycobacterium tuberculosis (Mtb)-injected (K1), Mtb-injected + OAT (anti-tuberculosis drugs), Mtb-injected + OAT + 1,000 IU vitamin D biscuit (D1), and Mtb-injected + OAT + 2,000 IU vitamin D biscuit (D2), and were observed for a total of 46 days. H37Rv Mycobacterium tuberculosis (Mtb) was injected into as much as 106 colonies/ml of 100 µL. Complete blood count was measured using the HEMAVET method, albumin and total protein were determined using spectrophotometry, and C-reactive protein (CRP) was analyzed using enzyme-linked immunosorbent assay (ELISA). Although product administration did not show a significant impact towards erythrocytes (p>0.05), it was still able to improve BMI within normal limits, increase albumin and total serum protein values, maintain leukocyte, hemoglobin, and hematocrit within standard values, lower CRP levels.