Arif Utama Rambe
Department of Informatics Engineering, UIN Sultan Syarif Kasim Riau, Pekanbaru 28293, Indonesia

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Application of the smote and backpropagation neural network (BPNN) techniques in the classification of non-alcoholic fatty liver disease (NAFLD) Arif Utama Rambe; Reski Mai Candra; Fitri Insani; Rahmad Abdillah; Siska Kurnia Gusti
Science, Technology, and Communication Journal Vol. 6 No. 3 (2026): SINTECHCOM Journal (June 2026)
Publisher : Lembaga Studi Pendidikan dan Rekayasa Alam Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59190/stc.v6i3.399

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a liver disorder with a high global prevalence and a significant mortality risk. However, clinical NAFLD datasets often exhibit severe class imbalance, causing machine learning models to become biased toward the majority class. This study aims to classify the mortality risk of NAFLD patients using the backpropagation neural network (BPNN) algorithm combined with the synthetic minority over-sampling technique (SMOTE). To ensure model validity, the follow-up time variable (futime) was excluded to prevent data leakage. The experiments were conducted by comparing different data split ratios (70:30, 80:20, and 90:10) as well as various hidden layer configurations and learning rates. The experimental results indicate that, without SMOTE, the model was trapped in the illusion of high accuracy (92%) while failing to detect mortality cases effectively (recall < 15%). In contrast, the application of SMOTE significantly improved the recall value, reaching 79.85% under the 80:20 data split scenario. These findings demonstrate that the integration of SMOTE and BPNN is highly effective in minimizing missed diagnoses (false negatives) in imbalanced medical datasets.