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All Journal Jurnal Ilmiah Dr. Aloei Saboe
Ryski Rahmawaty Lahmudin
Universitas Bina Mandiri Gorontalo, Indonesia
Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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LITERATURE STUDY ON PHARMACOKINETIC PROFILES OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN GERIATRIC POPULATIONS Ryski Rahmawaty Lahmudin
Jurnal Ilmiah dr. Aloei Saboe Vol. 4 No. 1 (2024): Jurnal Ilmiah dr. Aloei Saboe
Publisher : LP2M Universitas Bina Mandiri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47918/jias.v4i1.1747

Abstract

This literature review examines the pharmacokinetic profile of nonsteroidal anti-inflammatory drugs (NSAIDs) in the geriatric population. Given the high prevalence of chronic conditions requiring NSAID use among the elderly, understanding the pharmacokinetic alterations due to physiological changes in this age group is crucial. The review highlights key findings from recent studies, showing that elderly patients are more susceptible to adverse effects due to altered drug absorption, distribution, metabolism, and excretion. It also emphasizes the importance of appropriate dosing, careful monitoring, and the potential of alternative therapies like warm moringa leaf compresses for managing pain. Furthermore, the review underlines the necessity for improved prescribing practices and the development of detailed clinical guidelines to ensure the safe and effective use of NSAIDs in the geriatric population.
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