Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal BIOTROPIA - The Southeast Asian Journal of Tropical Biology
Titi Candra Sunarti
Department of Engineering and Department of Agroindustrial Technology, Faculty of Agricultural Technology, Institut Pertanian Bogor, Bogor 16680
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Veterinary

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
ANTIBREAST CANCER ACTIVITY OF NANOPROPOLIS INDONESIA ON INDUCED MAMMARY GLAND TUMOR BY DMBA IN VIRGIN SPRAGUE–DAWLEY RATS Akhmad Endang Zainal Hasan; Djumali Mangunwidjaja; Titi Candra Sunarti; Ono Suparno; Agus Setiyono
BIOTROPIA Vol. 23 No. 1 (2016): BIOTROPIA Vol. 23 No. 1 June 2016
Publisher : SEAMEO BIOTROP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.285 KB) | DOI: 10.11598/btb.2016.23.1.473

Abstract

The objective of this study was to determine the effect of nanopropolis on DMBA-induced mammary tumors in rats. After the first tumor appearance, twenty-eight rats were divided into seven groups. Groups 1, 2, and 3 served as recipients of nanopropolis treatments at dosages of 8, 32, and 56 μg/mL, respectively. Group 4 received propolis at 233 μg/mL, Group 5 served as the treatment control, Group 6 received DMBA only, and Group 7 served as the normal control. The effects of nanopropolis at 32 μg/mL and propolis at 233 μg/mL were similar in reducing tumor size, healing wounds caused by the tumor, and eliminating cancer cells. Furthermore, the study suggested a relationship between particle size of the absorbent material and its effectiveness. Overall, nanopropolis was very effective in treating mammary gland tumors and breast cancer even at small concentrations.
Co-Authors Agus Setiyono Akhmad Endang Zainal Hasan Djumali Mangunwidjaja Ono Suparno