Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal agriTECH Majalah Obat Tradisional
Rizal Maarif Rukmana
Research Center for Pharmaceutical Ingredients and Traditional Medicine, Research Organization for Health, National Research and Innovation Agency (BRIN), Bogor, 16911
Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Antibacterial Activity of Myrmecodia pendens (Ant Nest Plant) against Multidrug Resistance Bacteria from Clinical Samples Muhammad Evy Prastiyanto; Aditya Rahman Ernanto; Sri Darmawati; Endang Tri Wahyuni Maharani; Arif Mulyanto; Rizal Maarif Rukmana; Wahyu Aristyaning Putri; Lia Kusmita; Shiv Kumar Sah; Daniel Geleta
Majalah Obat Tradisional Vol 31, No 1 (2026)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.110761

Abstract

The emergence of multidrug-resistant (MDR) bacteria causes a substantial barrier to treatment, demanding the development of new antibacterial medicines. Myrmecodia pendens (ant nest plant), an indigenous medicinal species, is esteemed for its potential medicinal properties. This study aimed to examine the antibacterial efficacy of M. pendens extracts against MDR bacterial strains (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Citrobacter freundii, and Pseudomonas aeruginosa) obtained from clinical samples. Extracts were prepared via maceration using ethanol, chloroform, and n-hexane solvents. Antibacterial efficacy was evaluated using the agar diffusion method, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) assays. The ethanol solvent extract exhibited the most significant antibacterial activity, particularly against P. aeruginosa, with an inhibition zone of 23.15 ± 0.21 mm at 100 mg/mL. The MIC and MBC values were 3.13 mg/mL and 12.5 mg/mL, respectively. The chloroform and n-hexane extracts showed lower, but comparable, inhibitory effects against the tested strains. These findings provide compelling evidence that M. pendens extracts, especially the ethanol extracts, represent a promising source for developing alternative antibacterial agents to combat MDR infections.
Stigmasterol Degradation Kinetics and Organoleptic Alterations in Stored Stevia Simplicia (Stevia rebaudiana (Bertoni) Bertoni) Devi Safrina; Sofa Farida; Aditya Dwi Permana Putra; Rizal Maarif Rukmana; Muhammad Bakti Samsu Adi; Rantika Silfarohana
agriTECH Vol 46, No 3 (2026)
Publisher : Faculty of Agricultural Technology, Universitas Gadjah Mada, Yogyakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/agritech.116976

Abstract

Stevia rebaudiana is a natural sweetener that is increasingly valued for its bioactive compounds, particularly stigmasterol, which exhibits potent antioxidant and anti-inflamatory properties. This study aimed to evaluate the kinetics of stigmasterol degradation, moisture content, instrumental color changes, and organoleptic alterations in stevia simplicia stored over 35 months. Stigmasterol content was quantified using Thin Layer Chromatography (TLC) densitometry, moisture content was determined gravimetrically, and quality stability was assessed through instrumental colorimetric analysis and organoleptic evaluation (odor and flavor). The results showed that stigmasterol content decreased significantly from 7.30% at month 0 to below 4.00% within the first 12 months, eventually reaching approximately 1.30% at month 35 adhering to a first-order kinetic model. Conversely, moisture content increased steadily following zero-order kinetics (R² = 0.9184; k = 0.1715). Instrumental color analysis demonstrated a marked decrease in green-color intensity (µG) from 89.48 to 48.94, which coincided with a noticeable decline in organoleptic quality (odor and flavor). Overall, moisture accumulation during storage was strongly associated with accelerated stigmasterol degradation and sensory deterioration, emphasizing the critical need for moisture-retentive storage conditions to maintain the quality of stevia simplicia.
Co-Authors Aditya Dwi Permana Putra Aditya Rahman Ernanto Arif Mulyanto Daniel Geleta Devi Safrina Endang Tri Wahyuni Maharani Lia Kusmita Muhammad Bakti Samsu Adi Muhammad Evy Prastiyanto Rantika Silfarohana Shiv Kumar Sah Sofa Farida Sri Darmawati Wahyu Aristyaning Putri