Yuyun Nailufar
Universitas ‘Aisyiyah Yogyakarta

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Literature Review: Comparison of the Quality of Papanicolaou, Giemsa, and May-Grunwald Giemsa Staining in Pleural Effusion Specimens Winarti Nurhaliza; Yeni Rahmawati; Yuyun Nailufar
JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS Vol. 12 No. 2 (2025): Jurnal Kesehatan (Oktober 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/jurkes.v12i2.882

Abstract

Pleural effusion is a pathological condition characterized by fluid accumulation in the pleural cavity, which can occur due to infection, malignancy, or systemic disorders such as congestive heart failure. Cytological examination is an effective diagnostic method for detecting abnormal cells and malignancy in pleural effusion by reviewing the quality of staining results. This study aims to analyze and compare the staining quality of Papanicolaou, Giemsa, and May Grunwald Giemsa in pleural effusion cytology examination. The literature review results included 8 journals that met the inclusion criteria. These journals were obtained from the Google Scholar, PubMed, and Publish or Perish databases using the PICO search method and then selected based on inclusion and exclusion criteria using the PRISMA flow diagram. The results of the literature review showed that the Papanicolaou method provided clearer contrast between the nucleus and cytoplasm with a good background, Giemsa displayed cell morphology but the background was less clean, while May-Grunwald Giemsa showed stable staining results and good cell detail.
Identifikasi Kadar Pengawet Natrium Benzoate pada Saus Tomat yang Beredar di Wilayah Kabupaten Dompu Nurislamiah Nurislamiah; Sri Martuti; Yuyun Nailufar
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 6 No. 1 (2026): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v6i1.8780

Abstract

Tomato sauce is a popular processed food product often added with preservatives to extend shelf life. Sodium benzoate is one of the most commonly used preservatives; however, its use must comply with the maximum limit set by BPOM, which is 1000 mg/kg. Excessive intake may cause health problems such as carcinogenic benzene formation and nervous system disorders. This study aimed to identify the sodium benzoate content in tomato sauces sold in Dompu Regency and evaluate their compliance with food safety standards. A descriptive quantitative method with a cross-sectional approach was applied. Five brands of tomato sauce were randomly selected from markets and minimarkets, then analyzed at the Toxicology Laboratory of Universitas ‘Aisyiyah Yogyakarta using UV-Vis spectrophotometry. The results showed sodium benzoate levels of 69.25 mg/kg in sample A, 1,653 mg/kg in DB, 263.7 mg/kg in DM, 166.5 mg/kg in JT, and 1,028 mg/kg in ML. Two of the five samples (DB and ML) exceeded the maximum permissible limit. These findings indicate that some tomato sauce products in Dompu Regency do not meet food safety standards, highlighting the need for stricter supervision to protect consumers.