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All Journal Jurnal Sains Farmasi dan Kesehatan
Abdurrozzaq Hasibuan
Kesehatan Masyarakat, Fakultas Ilmu Kesehatan Masyarakat, Universitas Islam Negeri Sumatera Utara
Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Tinjauan Literatur Kualitatif tentang Dampak Paparan Bahan Kimia terhadap Kesehatan Pekerja Industri Tiara Putri Azzahra Tamin; Abellia Putri; Tiara Khairani Br Purba; Abdurrozzaq Hasibuan
Jurnal Sains Farmasi Dan Kesehatan Vol. 3 No. 3 (2026): Januari - April
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v3i3.4441

Abstract

Chemical exposure in industrial environments is a major risk factor contributing to adverse health outcomes among workers. This study aims to analyze the impact of chemical exposure on industrial workers’ health through a qualitative literature review by examining scientific articles published between 2020 and 2025 from electronic databases such as Google Scholar and ResearchGate  . The findings indicate that exposure to chemicals such as benzene, mercury, organic solvents, and toxic gases exerts significant toxic effects on multiple physiological systems, including the respiratory, nervous, and reproductive systems, as well as vital organs such as the liver and kidneys, with primary exposure routes through inhalation, dermal contact, and ingestion. Most studies report exposure levels within moderate to high-risk categories, with the potential to cause both acute and chronic health effects, including degenerative diseases and malignancies. Determinant factors influencing risk levels include duration of exposure, compliance with personal protective equipment (PPE) usage, workplace ventilation conditions, and workers’ knowledge levels. Therefore, comprehensive risk control measures are required through the implementation of the hierarchy of controls, strengthening occupational health and safety (OHS) management systems, and enhancing worker education and training to establish a safe, healthy, and sustainable working environment.
Literatur Review : Toksikologi Industri Dan Keselamatan Kesehatan Kerja Dalam Pengendalian Paparan Bahan Kimia Pada Sektor Manufaktur Dan Rumah Sakit: Indonesia Mardiah Sitorus; Rezki Alya Mawaddah Sitorus; Selamat Ariady Tampubolon; Abdurrozzaq Hasibuan
Jurnal Sains Farmasi Dan Kesehatan Vol. 3 No. 3 (2026): Januari - April
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v3i3.4451

Abstract

Industrial toxicology is a branch of science that plays a crucial role in identifying, analyzing, and controlling the impact of chemical exposure on worker health, particularly in the manufacturing and hospital sectors, which have high risk levels. Exposure to chemicals such as organic solvents, heavy metals, disinfectants, and cytotoxic drugs can cause both acute and chronic health problems if not managed properly. This study aims to examine the role of industrial toxicology in controlling chemical exposure and the application of Occupational Safety and Health (OHS) principles to minimize worker health risks. The method used is a literature review by analyzing various national and international journals from the last five years that are relevant to the research topic. The results of the study indicate that effective control of chemical exposure must refer to the hierarchy of control, including elimination, substitution, engineering, administrative control, and the use of personal protective equipment (PPE). In addition, the implementation of a structured OHS management system, continuous worker training, and routine monitoring of the work environment have been proven to reduce exposure levels and the risk of occupational diseases. These findings confirm that the integration of industrial toxicology with a comprehensive OHS system is not merely a formality, but a fundamental necessity for creating a safe, healthy, and productive work environment. Without disciplined controls, long-term risks to workers will continue to be overlooked, leading to a decline in the quality of human resources.
Co-Authors Abellia Putri Mardiah Sitorus Rezki Alya Mawaddah Sitorus Selamat Ariady Tampubolon Tiara Khairani Br Purba Tiara Putri Azzahra Tamin