Mathematics anxiety in statistics learning remains a problem that has rarely been specifically addressed through learning media that explicitly integrate computational thinking. This study aims to develop a Computational Thinking-Integrated Statistics E-LKPD to reduce students' mathematics anxiety, using the ADDIE model, comprising the analyze, design, develop, implement, and evaluate stages. The research trial subjects were tenth-grade students of SMA Negeri 1 Mengwi. Validity data were obtained through validation by material and media experts, practicality data through the User Experience Questionnaire (UEQ), and effectiveness data through the Abbreviated Math Anxiety Scale (AMAS). Data were analyzed using the average-scoring formula, the UEQ data analysis tool, and a paired-samples t-test. The results showed that the developed E-LKPD had very good quality. Material expert validation scored 0.98 and media expert validation 0.91, both categorized as very valid. The practicality showed excellent clarity, good efficiency, accuracy, stimulation, and novelty, and an above average attractiveness. The effectiveness test showed a decrease in the mean mathematics anxiety score from 29.86 at pretest to 26.21 at posttest, with a paired samples t-test significance value of 0.001 (< 0.05). Thus, the product meets the criteria of validity, practicality, and effectiveness, making it feasible for use in tenth-grade statistics learning.