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The Wound Healing Potential of Honey and Propolis from Stingless Bees in Acute Wounds Viky Hibatu Wafi; Yudhy Arius; Ivan Joalsen Mangara Tua; Swandari Paramita; Endang Sawitri
MAHESA : Malahayati Health Student Journal Vol 5, No 7 (2025): Volume 5 Nomor 7 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i7.18933

Abstract

ABSTRACT Honey and propolis from stingless bees have been reported to promote wound healing due to their anti-inflammatory, antioxidant, antibacterial, and moisturizing activities. However, variations in compounds and biological activities of these products can arise due to geographical and bee origin differences. This study aimed to investigate the wound healing potential of stingless bee honey and propolis from East Kalimantan in an acute wound animal model. Honey and propolis from stingless bees have been reported to promote wound healing due to its anti-inflammatory, antioxidant, antibacterial, and moisturizing activities. However, variation of compounds and biological activities of these products can arise due to geographical and bee origin differences. This study aimed to investigate the wound healing potential of stingless bee honey and propolis from East Kalimantan in acute wound animal model. A post-test only control group design was employed in this study. Fifteen Wistar rats were divided into 3 groups, i.e., a control receiving tulle and treatment groups receiving stingless bee honey and propolis, respectively. Wound healing activity was evaluated from wound diameter changes and histological evaluations following hole punch wound. Kruskal Wallis test results showed no significant changes in the proliferation phase of wound healing, as reflected by the diameter changes (p = 0.989), the rate of histopathological re-epithelization (p = 0.730) as well as number of fibroblasts (p = 0.779), collagen (p = 0.779), and neovascularization (p = 0.756) among the groups. Honey and propolis from stingless bees have the potential to treat acute wounds in the proliferation phase where their wound healing properties are equivalent to tulle. Keywords: Acute Wound, Stingless Bee, Honey, Propolis.
Association of Sociodemographic Factors with Health Protocol Compliance and Metabolic Profile Among Patients with Diabetic Retinopathy Yuliana Rahmah Retnaningrum; Yuniati; Nur Khoma Fatmawati; Endang Sawitri; Amalia Aswin; Rudi Saputra
Journal of Public Health Sciences Vol. 5 No. 03 (2026): In Press - Journal of Public Health Sciences
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/IISTR.jphs.002310

Abstract

Diabetic retinopathy is a major microvascular complication of diabetes mellitus and is closely related to metabolic disturbances and sociodemographic factors. This study aimed to analyze the association between sociodemographic characteristics, health protocol compliance, and metabolic profile parameters among patients with diabetic retinopathy. An analytical observational study with a cross-sectional design was conducted among 45 diabetic retinopathy patients at two hospitals in Samarinda, Indonesia, during November 2020. Sociodemographic data, serological status, mask types, health protocol compliance scores, and metabolic profile parameters were collected. Female participants slightly predominated (53.3%), and most participants were aged <60 years (71.1%). Educational level was significantly associated with health protocol compliance score (p = 0.008), with higher educational attainment related to better health protocol compliance. Age was significantly associated with HbA1c (p = 0.006), FBG (p = 0.008), and 2hPPBG (p = 0.045). Occupation was significantly associated with TC/HDL (p = 0.008) and LDL/HDL ratios (p = 0.019), while gender was associated with the TC/HDL ratio (p = 0.048). No significant associations were identified between serological status or mask types and metabolic profile parameters. These findings suggest that sociodemographic characteristics, particularly educational level, age, and occupation, may be associated with differences in health behavior and metabolic profiles among patients with diabetic retinopathy.