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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Agrium
Nurahmi, Nurahmi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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Pengaruh Lama Blansir Dan Suhu Pengeringan Terhadap Kualitas Bubuk Cabai Merah (Capsicum annuum L.) Hayati, Hayati; Nurahmi, Nurahmi; R, Yolanda
Agrium Vol 20 No 3 (2023)
Publisher : Faculty of Agriculture, Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/agrium.v20i3.13024

Abstract

Penelitian ini bertujuan untuk mempelajari pengaruh lama blansir dan suhu pengeringan terhadap kualitas bubuk cabai merah varietas TM-999. Cabai merah merupakan komoditas hortikulturabernilai ekonomi tinggi yang digunakan luas dalam industri makanan dan farmasi. Cabai ini kayaakan nutrisi penting seperti karbohidrat, lemak, protein, kalsium, vitamin A, B1, dan C, serta memiliki potensi sebagai agen anti kanker berkat kandungan lasparaginase. Penelitian dilakukandi Laboratorium Teknologi Benih Jurusan Agroteknologi Fakultas Pertanian Universitas SyiahKuala, Banda Aceh, selama Februari hingga Mei 2023. Penggunaan berbagai peralatan laboratorium seperti oven, kipas angin, ayakan 60 mesh, dan lainnya, mendukung penelitian ini. Sementara itu, bahan yang digunakan meliputi 9 kilogram cabai merah varietas TM-999 yang dipanen setelah mencapai usia 90 hari, serta bahan kimia tertentu. Penelitian mengikuti desain Rancangan Acak Lengkap (RAL) dengan variasi lama blansir (0, 2, dan 3 menit) dan suhu pengeringan (50°C, 55°C, dan 60°C). Hasil penelitian menunjukkan bahwa lama blansir berpengaruh signifikan terhadap warna a dan aroma, dengan lama blansir 3 menit memberikan kualitas bubuk cabai merah optimal. Suhu pengeringan berpengaruh pada kadar vitamin C, dengan suhu 50°C menjadi yang terbaik. Selain itu, penelitian ini tidak menemukan interaksi yang signifikan antara lama blansir dan suhu pengeringan terhadap kualitas cabai merah. Hasil ini memberikan panduan berharga untuk meningkatkan proses pengeringan dan kualitas bubuk cabai merah dalam aplikasi industri pangan dan farmasi.
An Atherogenic Index of Plasma in Type 2 Diabetes Mellitus with and without Coronary Artery Disease Oktarina, Nur Hasni; Kurniawan, Liong Boy; Nurahmi, Nurahmi
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 2 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i2.2280

Abstract

Chronic hyperglycemia causes an increase in glycosylation products that induce inflammation and injury to the arterial wall, which will cause changes in the vascular tissue resulting in atherosclerosis. The Atherogenic Index of Plasma (AIP) has been suggested as a biomarker for atherosclerosis and has demonstrated a strong correlation with other atherosclerosis indices, including small dense LDL and LDL cholesterol. This study aimed to determine the AIP in Type 2 Diabetes Mellitus (T2DM) patients with and without Coronary Artery Disease (CAD) complications. A retrospective cross-sectional study using medical record data of 73 T2DM patients without CAD complications and 73 T2DM patients with CAD complications at Dr. Wahidin Sudirohusodo General Hospital was carried out from January to December 2022. The diagnosis of T2DM and CAD was based on the clinician's diagnosis. An atherogenic index of plasma was calculated as log (triglyceride/HDL cholesterol). Samples were analyzed using SPSS version 25, using the Kolmogorov-Smirnov statistical test to assess data normality, Mann-Whitney test, the Receiver Operating Characteristics (ROC) curve to assess Area Under Curve (AUC), and a determination of cut-off values. Statistical test results with p-values <0.05 were reported as significant. Atherogenic index of plasma values was significantly higher in T2DM with CAD complications than without CAD complications (0.51±0.25 vs. 0.30±0.11, p<0.001). The ROC curve analysis showed an optimal cut-off value of 0.36 to predict T2DM with CAD with 71% sensitivity, 62% specificity, and 66% accuracy. There was a significant association between high AIP values and CAD complications in T2DM. An atherogenic index of plasma value can be used to predict T2DM with CAD.
Analysis of Hemostasis Function in Obesity Subjects Using Thromboelastography Kasimat, Maria Magdalena; Nurahmi, Nurahmi; Kurniawan, Liong Boy
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 2 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i2.2326

Abstract

Hemostasis disorders can be caused by obesity, associated with decreased fibrinolysis, increased fibrinogen and plasminogen activator inhibitor activity. Thromboelastography shows hemostasis function from clots formation to the fibrinolysis process. This study aimed to determine the hemostasis function in obese compared to non-obese subjects using thromboelastography. A cross-sectional study at the Clinical Pathology Laboratory Installation of Dr. Wahidin Sudirohusodo Hospital. The study population was non-diabetic subjects who agreed to participate. Hemostasis tests using thromboelastography and analysis of R, K, Alpha angle, and Maximum Amplitude (MA) values were performed. The total number of research subjects was 40 subjects, consisting of 20 obese subjects and 20 non-obese subjects. In these two groups, there were no differences in the K (2.92±1.3 vs. 2.64±1.1, p=0.461), Alpha angle (54.18±9.2 vs. 56.29±10.5, p=0.372), and MA values (57.99±10.3 vs. 54.93±8.2, p=0.766). The obese group got a higher R-value than the non-obese group (7.45±1.8 vs. 4.11±1.2. p=0.006) The R-value was higher (elongated) in the obese subject than the non-obese subject. In the two subject groups, there were no differences in the K, Alpha angel, and MA values.
Correlation between Serum Visfatin Level with Glycemic Control in Type 2 Diabetes Mellitus Subjects Fadillah, Ismirayanti; Nurahmi, Nurahmi; Kurniawan, Liong Boy
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 3 (2025)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i3.2304

Abstract

Visfatin is an endocrine, paracrine, and autocrine peptide that functions in cell proliferation and glucose metabolism. Visfatin has insulin-like characteristics. Serum visfatin level is increased in diabetes mellitus subjects despite other contradicting results. The study aimed to investigate the correlation between serum visfatin level and glycemic control in subjects with type 2 diabetes mellitus. The study was a cross-sectional involving all patients diagnosed with type 2 diabetes mellitus at Dr. Wahidin Sudirohusodo Hospital as the research population. The research sample was all patients with type 2 diabetes mellitus and had HbA1c examination results that met the inclusion criteria. The level of serum visfatin was measured using the ELISA technique from Biobase. Data were statistically analyzed using Kolmogorov-Smirnov test, Mann-Whitney test, and Spearman’s correlation test. The research sample consisted of 70 subjects who were grouped into good glycemic control and poor glycemic control based on HbA1c values. Serum level of visfatin did not significantly differ between those with good and poor glycemic control (0.54±0.58 vs. 0.51±0.45 ng/mL, p=0.990). The level of serum visfatin and HbA1c value did not significantly correlate (p=0.813).  
Co-Authors Fadillah, Ismirayanti Hayati Hayati Kasimat, Maria Magdalena Liong Boy Kurniawan, Liong Boy Oktarina, Nur Hasni R, Yolanda