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All Journal Biocaster : Jurnal Kajian Biologi
Veronika P. Sinta Mbia Wae
Program Studi Pendidikan Biologi, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Flores, Jalan Sam Ratulangi, Ende, Nusa Tenggara Timur 86318, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology

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Pengaruh Radiasi terhadap Struktur dan Fungsi Sel Tiara Novianti Dadi Lado; Lidia Delvina Bhoki; Santiana E. Rithi; Tersius Soba; Veronika P. Sinta Mbia Wae
Biocaster : Jurnal Kajian Biologi Vol. 6 No. 2 (2026): April
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v6i2.993

Abstract

Ionizing and non-ionizing radiation are widely used in health, industry, scientific research, and communication technology, but their use also has the potential to pose biological risks to humans. Therefore, a comprehensive understanding of the mechanisms of radiation interaction with biological tissues and their health implications is crucial. This study aims to systematically examine the biological effects of ionizing and non-ionizing radiation on human health, as well as the safety principles applied in their use. The research method used is a literature review by examining scientific articles, reports from international institutions, and relevant publications that discuss radiation exposure, biological impacts, and aspects of radiation protection. The results of the study indicate that ionizing radiation, such as X-rays and gamma rays, has the ability to ionize atoms and molecules, thus potentially causing DNA damage that can trigger deterministic and stochastic effects, including an increased risk of cancer. Although radiation doses in medical diagnostic procedures are generally below the hazardous threshold, the application of radiation protection principles in the form of justification, optimization, and dose limitation remains a key factor in ensuring the safety of patients and healthcare workers. While non-ionizing radiation from telecommunications devices does not cause ionization, at high exposure levels it can cause thermal effects on biological tissue, although most epidemiological studies have not shown a consistent link with an increased risk of cancer. Exposure to cosmic radiation during commercial flights and at high altitudes has the potential to cause dose accumulation, which requires special attention. The conclusion of this study emphasizes that radiation use must be accompanied by adequate scientific understanding, long-term risk evaluation, and the implementation of strict safety policies to ensure that the benefits of radiation use outweigh the risks.
Autofagi : Mekanisme Pemeliharaan Diri Sel dalam Kondisi Stres Kanisia Petra Seto Lejo; Jihan Pramitha Kanggo; Maria Ventiana Wea; Alfa Zaki; Veronika P. Sinta Mbia Wae
Biocaster : Jurnal Kajian Biologi Vol. 6 No. 2 (2026): April
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v6i2.995

Abstract

Autophagy is a cellular mechanism in the form of degradation and recycling of intracellular components that plays an important role in maintaining cell homeostasis, especially when cells are under stress conditions such as nutritional limitations, oxidative stress, organelle damage, or pathogen attacks. Through this process, cells are able to survive by eliminating damaged or dysfunctional structures, while simultaneously reusing the degradation products as a source of energy and building blocks for new molecules. This study aims to examine the mechanism of autophagy, the molecular regulations involved, and its role in the response to various forms of cellular stress using a literature review method. Reference sources in this study come from relevant scientific articles and are accessed through PubMed, Scopus, and Google Scholar databases with a publication year range of 2015-2024. Articles are selected based on the main inclusion criteria, namely discussions on the molecular pathway of autophagy, the process of autophagosome formation, and the role of lysosomes in cellular degradation mechanisms. The study results indicate that autophagy is an essential adaptive mechanism primarily controlled by the mTOR and AMPK pathways in response to cellular stress. Adaptive autophagy plays a crucial role in maintaining cell stability and survival, while autophagy dysfunction or uncontrolled activation is pathological and contributes to the development of various diseases, making autophagy a strategic therapeutic target. Furthermore, disruption of the autophagy process is known to be closely associated with the development of various degenerative and metabolic diseases, making autophagy a potential target in the development of biomedical therapeutic strategies.
Tradisi Reba dan Konservasi Uwi (Dioscorea esculenta): Kajian Etnobotani Masyarakat Adat Desa Binawali Kabupaten Ngada Veronika P. Sinta Mbia Wae; Anastasia Modesta Nena; Elisabet Oka; Genoveva Angela Surideo
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.435

Abstract

This study focuses on the Reba tradition and the conservation of yam (Dioscorea esculenta) in Binawali Village, Ngada Regency, through an ethnobotanical approach. The Reba tradition is an annual harvest ritual in which the Ngada ethnic community honors yam as a symbol of life, prosperity, and ancestral heritage. Yam is considered the "bread of life" and their main staple food long before rice and corn were known. Despite having high historical and spiritual value and being easy to cultivate, the utilization of yam is still low, due to the lack of interest of the younger generation and the suboptimal economic utilization which threatens its sustainability as a local agrobiodiversity. This study aims to describe the symbolic meaning of yam in the Reba tradition and examine how the tradition contributes to local and sustainable yam conservation. This study uses a qualitative method with an ethnographic approach, through participant observation, interviews, and documentation of traditional elders, village heads, farmers, and community members for data collection. The results show that the Reba tradition not only functions as an expression of spiritual culture, but also as a mechanism for in situ conservation of yam through customary regulations, management of inherited land, and transmission of local knowledge between generations. This finding emphasizes the importance of strengthening customary institutions as a pillar in community-based agrobiodiversity conservation.
Potensi Tabha Lame sebagai Pangan Fungsional Tradisional untuk Mendukung Laktasi: Kajian Etnobotani di Suku Ua Kabupaten Nagekeo Veronika P. Sinta Mbia Wae; Anjelina Larici Babo; Maria Fransiska Owa; Yuliana Bupu; Bonefasia Gabriela Noni Ngange; Maria Prima Owa
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.515

Abstract

Tabha Lame is a traditional food of the Ua Tribe in Nagekeo Regency which has been traditionally believed to increase breast milk production. However, this belief has never been scientifically studied and systematically documented, especially regarding its nutritional function and ethnobotanical value. This study aims to identify the composition of ingredients, processing, and nutritional potential of Tabha Lame as a locally based functional food. This study was conducted using a qualitative descriptive approach through interviews and field documentation methods with traditional leaders and women who possess traditional knowledge. The results show that Tabha Lame is made from local ingredients, such as: jali (Coix lacryma-jobi), moringa leaves (Moringa oleifera), peanuts (Arachis hypogaea), and coconut milk cooked using the Dhedhu Zaka technique. The content of phytoestrogens, iron, vegetable protein, vitamin A, and unsaturated fatty acids in these ingredients contribute to supporting the lactation process. The slow cooking process maintains micronutrients, while the symbolic presentation demonstrates the integration between nutrition and culture. The conclusion of this study confirms that Tabha Lame is a locally based functional food with potential for development in community-based nutritional interventions for breastfeeding mothers and the preservation of traditional knowledge.
Co-Authors Alfa Zaki Anastasia Modesta Nena Anjelina Larici Babo Bonefasia Gabriela Noni Ngange Elisabet Oka Genoveva Angela Surideo Jihan Pramitha Kanggo Kanisia Petra Seto Lejo Lidia Delvina Bhoki Maria Fransiska Owa Maria Prima Owa Maria Ventiana Wea Santiana E. Rithi Tersius Soba Tiara Novianti Dadi Lado Yuliana Bupu