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All Journal Biodiversitas Journal of Biological Diversity
MUHAMAD SYUKUR
Department of Agronomy and Horticulture, Faculty of Agriculture, Institut Pertanian Bogor. Jl. Meranti, Kampus IPB Dramaga, Bogor 16680, West Java, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology

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GC-MS analysis of rhizome ethanol extracts from Curcuma aeruginosa accessions and their efficiency activities as anticancer agent Waras Nurcholis; NURUL KHUMAIDA; MARIA BINTANG; MUHAMAD SYUKUR
Biodiversitas Journal of Biological Diversity Vol. 22 No. 3 (2021)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d220313

Abstract

Abstract. Nurcholis W, Khumaida N, Bintang M, Syukur M. 2021. GC-MS analysis of rhizome ethanol extracts from Curcuma aeruginosa accessions and their efficiency activities as anticancer agent. Biodiversitas 22: 1179-1186. This work aimed to evaluate the bioactive compounds and anticancer activity in rhizome extract of ten Curcuma aeruginosa accessions to explore their pharmacological values. The GC-MS analysis was used to identify bioactive compounds. The cytotoxic activity was performed against MCF-7 (Human breastadeno carcinoma) and Vero cell lines using MTT assay. The GC-MS analysis revealed 71 of the compounds as sesquiterpenes (36), monoterpenes (20), phenolics (5), diterpenes (4), phenanthrene (1), tetrapeptides (1), oxazole (1), triazine (1), piperidine (1), and oxygenated hydrocarbons (1). The isocurcumenol was the most dominant metabolite in ethanol extract of C. aeruginosa rhizome, with the highest produced by KP accession (22.01%) followed MD accession (21.12%). However, camphor and ?-elemene were the metabolites produced by all accessions studied. In the Vero cell line as a normal cell, the cytotoxic activity varied from 13.28% (MD) to 45.17% (PW). Furthermore, the cytotoxic activity ranged from 1.16% (LC) to 49.70% (MD) against the MCF-7 cell line. The highest anticancer activity was produced in MD accessions; thus, it can be used as a source of quality raw materials for the pharmaceutical and food industry. Besides that, it can also be further developed to obtain superior varieties through plant breeding programs.
Morpho-physiological seed diversity and viability of Indonesian cowpea (Vigna unguiculata) ENY WIDAJATI; MUHAMAD SYUKUR; RIDWAN DIAGUNA; OKTI SYAH ISYANI PERMATASARI; ARYA WIDURA RITONGA; ZULFIKAR DAMARALAM SAHID; GAGAD RESTU PRATIWI; ANDI NADIA NURUL LATHIFA HATTA
Biodiversitas Journal of Biological Diversity Vol. 24 No. 10 (2023)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d241013

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Abstract. Widajati E, Syukur M, Diaguna R, Permatasari OSI, Ritonga AW, Sahid ZD, Pratiwi GR, Hatta ANNL. 2023. Morpho-physiological seed diversity and viability of Indonesian cowpea (Vigna unguiculata). Biodiversitas 24: 5319-5327. Cowpea is a legume with a potential nutritional content almost equivalent to soybeans; it can be developed as a substitute agent for raw materials for food processing. One of the factors in obtaining high cowpea production is to use of quality seeds. Our study aimed to evaluate the performance and morpho-physiological correlations and viability of cowpea seed collections from IPB University Bogor and the Indonesian Research Institute of Legume. We used ten genotypes of cowpea, which had superior seed information. The results showed that the ten cowpea genotypes had superior morpho-physiological and seed viability. The seed germination percentage was categorized as medium-high (>60%). Eight cowpea genotypes were grouped into one major group based on morpho-physiological characteristics and viability. Furthermore, positive correlations were found between the observed variables of seed viability (seed germination, seed growth speed, and seed vigor index). Our research results are useful as a source of genetic diversity for plant breeders in developing new superior varieties in the future. In addition, agronomists can use this information to plant cowpeas based on planting location.
Co-Authors ANDI NADIA NURUL LATHIFA HATTA ARYA WIDURA RITONGA ENY WIDAJATI GAGAD RESTU PRATIWI MARIA BINTANG NURUL KHUMAIDA OKTI SYAH ISYANI PERMATASARI RIDWAN DIAGUNA Waras Nurcholis ZULFIKAR DAMARALAM SAHID