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THE IMPLEMENTATION STUDY OF STORING AND REPORTING OF NARCOTICS AND PSYCHOTROPICS AT PHARMACIES IN DENPASAR CITY, BALI PROVINCE I Made Arie Dharma Putra Nugraha; Kadek Hendra D; I Made Agus Gelgel Wirasuta
Journal Pharmaceutical Science and Application Vol. 3 No. 1 (2021): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p02

Abstract

Introduction: Storage and reports of narcotics and psychotropic in pharmacy must be carried out according to standard operating procedures which are based on legislation on maintaining safety, efficacy, and quality of the drugs. Objective: This study aimed to observe the implementation process of narcotics and psychotropic storing and reporting in accordance to the law in force in several pharmacies in Denpasar City. Methods: Five biggest pharmacies located in Denpasar City were picked by purposive sampling method. This study used a descriptive observational method to provide a brief overview of the term and condition of narcotics and psychotropic storing and reporting that implemented in real-time in the pharmacies. Results: Overall, the study revealed that the majority of pharmacies were successfully in term of fulfilling the various aspects of narcotics and psychotropic storing and reporting, including the storage of drugs at the special cabinets, in special the implementation process of narcotics and psychotropic that cited in the Regulation of The Minister of Health of the Republic of Indonesia Number 73 of conditions according to safety and stability, FEFO and FIFO systems, manual and electronic stock cards system, separation of damaged and/or expired drug, inventory stock, and compliance and completeness of reporting using SIPNAP. Conclusion: Responsible pharmacist must always evaluate the storage and reporting of narcotics and psychotropic in the pharmacy to guarantee quality and maintain suitability of the pharmaceutical services process according to established standards. Keywords: forensic pharmacy; storing and reporting; narcotics and psychotropic; legislation
MONITORING DRUG THERAPY IN X’s PHARMACY IN BADUNG REGENCY Luh Pratiwi Diva Yanti; I Made Agus Gelgel Wirasuta; Luh Rai Maduretno Asvinigita
Journal Pharmaceutical Science and Application Vol. 3 No. 1 (2021): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i01.p03

Abstract

Background: Monitoring drug therapy based on Permenkes RI No. 73 of 2016 is one of the pharmaceutical care standards in pharmacy practice. Monitoring drug therapy is a process that includes activities to ensure safe, effective and rational drug therapy for patients. Patients who receive drug therapy are at risk of experiencing drug-related problems. Objective: This study aims to determine the implementation of monitoring drug therapy in one pharmacy in Badung Regency. Methods: The type of research is a descriptive observational study conducted by interview session one pharmacist in X Pharmacy, then analyzed descriptively according to Permenkes RI No 73 of 2016. Results: The results showed that in January-June 2020 there were 34 patients with disease categories requiring monitoring drug therapy: 27 patients with asthma (79%), six patients with diabetes (18%), and one patient with tuberculosis (3%). Patients with the largest visits were geriatric, which were 19 out of 34 patients. Conclusion: The monitoring of drug therapy at Pharmacy X has fulfilled all the parameters in the Standard Operating Procedure (SOP) for the implementation of in Pharmacy based on Permenkes RI No.73 of 2016. Keywords: Monitoring drug therapy, Implementation, Pharmacy, Pharmacist
STUDY OF PHARMACEUTICAL INVENTORY CONTROL SYSTEM IN SEVERAL PHARMACIES IN KARANGASEM, BALI I Made Ari Anata; I Made Agus Gelgel Wirasuta
Journal Pharmaceutical Science and Application Vol. 3 No. 2 (2021): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i02.p02

Abstract

The control of pharmaceutical products is one of the pharmaceutical services at the Pharmacy that is regulated in Permenkes RI No. 73 of 2016. The pharmacy control of each pharmacy must always apply the principles stated in the Good Pharmacy Practice (GPP) guidelines. GPP is a pharmaceutical practice that responds to the needs of people who use pharmacist services to provide optimal and evidence-based care. This study aims to determine the system of one of the pharmaceutical service standards, namely the control of pharmaceutical products in several pharmacies in Karangasem, Bali. This type of research is observational descriptive. Data retrieval is carried out in a retrospective manner related to the pharmaceutical product control system in the form of an order or procurement, dispensing, and handling system. Most pharmacies are researched to apply the same control system in the procurement and spending of pharmaceutical products. Only the pharmaceutical product system for handling parts has a slight difference in each pharmacy. Keywords: forensics; control; pharmaceutical products; pharmacies; pharmacists
THE IMPLEMENTATION OF INDONESIA HEALTH MINISTER REGULATION RELATED TO STERILIZED DISPENSING IN "X" HOSPITAL IN GIANYAR-BALI Ni Luh Putu Lestari Dewi; Ni Made Ari Ginarsih; I Made Agus Gelgel Wirasuta
Journal Pharmaceutical Science and Application Vol. 3 No. 2 (2021): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2021.v03.i02.p04

Abstract

The application of Regulation of the Minister of Health Number 72 of 2016 is very important to be implemented in every Pharmacy Installation in a hospital, one of which is in the clinical pharmacy service section, namely dispensing sterile preparations to avoid the possibility of medication errors. The research aimed to find out how the implementation of Regulation of the Minister of Health Number 72 of 2016 stipulated in the basic guidelines of aseptic techniques related to space, equipment, and the implementation of dispensing sterile preparations with its practice in Hospital "X" Gianyar, Bali. This research used Sequential Explanatory design by combining quantitative and qualitative methods. The results of quantitative research with a checklist found the percentage of completeness of the room and equipment by 100%, while the conformity of the practice with the guidelines of 76.48% is appropriate. The results of qualitative research with triangulation matrices that practice is by the guidelines. Dispensing sterile preparations at the Hospital "X" is following the basic guidelines of aseptic techniques that refer to Regulation of the Minister of Health Number 72 of 2016. Keywords: implementation; regulation; dispensing; sterile preparations; guidelines; medication errors
IMPLEMENTATION OF IMAGE ANALYSIS FROM THIN LAYER CHROMATOGRAM OF PURPLE SWEET POTATO LEAF EXTRACT IN CHEMICAL FINGERPRINTING Ni Putu Dinda Mirayanti; Putu Sanna Yustiantara; I Made Agus Gelgel Wirasuta
Journal Pharmaceutical Science and Application Vol. 5 No. 2 (2023): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Pharmacy Department, Math and Sciences Faculty, Udayana Univerity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2023.v05.i02.p01

Abstract

Background: Purple sweet potato (Ipomoea batatas L.) is a crop that contains rich amounts of anthocyanins and flavonoids. For maintaining its quality in preparations, fingerprint analysis using Thin Layer Chromatography (TLC) is commonly used. Objective: In this study, image analysis was implemented on the chromatogram to develop fingerprint profiles of the leaves of various types of purple sweet potatoes. Methods: Fingerprint analysis and acquisition of data were carried out by combining modern TLC equipment with software for image analysis. The in-situ fingerprint analysis using WinCats was compared with the image analysis results obtained in this study. The chemometric technique, cluster analysis, was performed to measure their difference in terms of sample classification. Cluster analysis was carried out to confirm that the clusters formed from image analysis were the same as those from WinCats. Results: The results obtained were two dendrograms, both showing the formation of two clusters, but with a different order of samples. This study concluded that the data obtained from image analysis using ImageJ software resulted in clustering with a similarity of 38.15%, while the data obtained from WinCats software resulted in classification with a similarity of 28.31%. Both methods had issues in determining the fingerprint profiles, as evidenced by the low level of similarity. Conclusion: These results indicate that image analysis has the potential to be implemented for fingerprint profile development. However, further analysis is needed to align the Rf values and confirm the compounds in the peaks. Keywords: Average linkage; Cluster analysis; Dendrogram; Purple sweet potato; Thin layer chromatography