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DAVINA ADIRA NATALIA
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology

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EVALUASI KETEPATAN PEMBERIAN ALTEPLASE DAN OUTCOME KLINIS PADA PASIEN STROKE ISKEMIK AKUT DENGAN TERAPI TROMBOLISIS DI RUMAH SAKIT X TAHUN 2024 DAVINA ADIRA NATALIA; Avianti Eka Dewi Aditya Purwaningsih; Francisca Tri Wituningtyas
Jurnal Farmasi Indonesia Vol 22 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v22i2.2674

Abstract

This study aimed to evaluate the timeliness of alteplase administration and clinical outcomes in acute ischaemic stroke patients at Hospital X in 2024. Using a retrospective analytic observational design, data were collected from patients' medical records with a focus on the timeliness of alteplase administration (<4.5 hours) and its impact on clinical outcomes. All patients (100%) received alteplase in a timely manner, according to AHA guidelines, with none receiving therapy after 4.5 hours. The results showed that the timeliness of alteplase administration had a significant effect on clinical outcome, with 90.9% of patients achieving a positive outcome. alteplase administration within the appropriate time window is critical for the clinical recovery of acute ischaemic stroke patients.
Co-Authors Francisca Tri Wituningtyas Purwaningsih, Avianti Eka Dewi Aditya