Female workers in the informal sector, such as traditional weavers, are vulnerable to occupational health and safety risks due to the lack of implementation of occupational health and safety (OHS), unsuitable working environments, and limited access to social security. Weak regulations and low participation of BPJS employment insurance have exacerbate this situation, so requiring a special attention to improve occupational health protection in the informal sector. This study aims to describe occupational health protection in the informal sector of traditional weavers in Karangasem, Bali. This was a descriptive study with a quantitative research method that involving 65 samples that selected by accidental sampling. The result showed that OSH aspects have not been optimally implemented, as evidenced by the lack of occupational safety and health training, the use of PPE, and noisy and non-ergonomic work environments. In addition, social protection is still lacking, as indicated by the low enrollment in BPJS employment insurance and insufficient concern for occupational health at the workplace. This study concludes that occupational health protection among the informal sector for female traditional weavers in Karangasem, Bali is still low, so that making the workers more vulnerable to occupational accidents and diseases. Therefore, it is recommended that workers be more proactive in understanding occupational risks and the importance of social protection. The owner, the government, and the agency of BPJS employment insurance need to collaborate in implementing OSH and expanding social security coverage for the informal workers.