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All Journal Journal of Multidisciplinary Science: MIKAILALSYS
Stephen Dio Titus
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Environmental Science Physics Social Sciences Other

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Enzymatic Bioremediation of Polyethylene Terephthalate Contaminated Environment Omachonu Alkali Odoma; Stephen Dio Titus; Silas Verwiyeh Tatah; Chukwuma Stephen Ezeonu
Journal of Multidisciplinary Science: MIKAILALSYS Vol 3 No 2 (2025): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v3i2.5612

Abstract

Enzyme-based bioremediation has emerged as a sustainable and eco-friendly approach to mitigating environmental pollution caused by plastic wastes, pesticides, heavy metals, and industrial effluents. This article explores recent advancements in enzymatic degradation, using polyethylene terephthalate hydrolase (PETases) and mono(2-hydroxyethyl) terephthalate hydrolase (MHETases) for polyethylene terephthalate (PET) breakdown, enzymatic mechanisms for bioleaching. PET is one of the most widely used synthetic plastics, contributing significantly to global plastic pollution due to its persistence in the environment. Conventional methods of PET disposal, such as incineration and landfilling, have proven to be inefficient and hazardous to the environment. In contrast, enzymatic biodegradation offers a promising eco-friendly solution to tackle PET biodegradation through the use of specialized enzymes like PETase and MHETase. We explore the mechanisms of PET biodegradation with focus on key enzymes and their catalytic pathways. Furthermore, the discovery, structure, and activity of PETase, the role of MHETase in processing degradation intermediates, and the contributions of corroborating enzymes such as cutinases, lipases, and esterases were also examined. Despite the promising potential of enzymatic PET degradation, several challenges remain, including enzyme, inefficiency in product recovery, and biosafety concerns associated with genetically modified organisms. In the same vein, regulatory hurdles and the need for standardization in bioremediation practices are discussed. Future research should focus on; the integration of enzymatic biodegradation into the circular bioeconomy, the use of artificial intelligence in enzyme design and the importance of global collaborations in advancing bioremediation strategies.
Prevalence of Trypanosoma Among Cattle Found in Grazing Hotspots in Jalingo Metropolis, Taraba State, Nigeria Sarah Baba Gurama; Wama Binga Emmanuel; Stephen Dio Titus; Vera Akwa Yafeh; David Christopher Bando; Munirah Ibrahim Foku; Usman Kesunga Yakubu
Journal of Multidisciplinary Science: MIKAILALSYS Vol 3 No 3 (2025): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v3i3.7458

Abstract

Bovine trypanosomiasis, commonly referred to as nagana, poses a significant threat to cattle populations across various regions in Africa, particularly in Nigeria. This disease caused by protozoan parasites of the genus Trypanosoma and transmitted by infected tsetse flies, results in extensive economic losses due to decreased productivity, fertility issues, and increased mortality rates among livestock. This study focuses on the prevalence of bovine trypanosomiasis in Jalingo, Taraba State, Nigeria a critical hub for cattle trade amidst the challenges posed by varied ecological factors and management practices that influence disease dynamics. Our research assessed 113 cattle samples collected from different grazing hotspots using both microscopy and polymerase chain reaction (PCR) techniques. The overall prevalence was found to be 17.7%, with notable concentrations of positive cases in specific locations. Factors such as age, breed, and the educational background of herders were significantly associated with infection rates. Notably, all positive cases were reported among herders lacking formal education, indicating a potential link between educational attainment and effective disease management. Furthermore, the White Fulani breed exhibited a higher susceptibility to the disease compared to other breeds evaluated. The results emphasize the necessity for targeted intervention strategies, including enhancing diagnostic capabilities, public awareness campaigns, and educational initiatives aimed at cattle herders. Strengthening healthcare infrastructure and ongoing research into disease transmission dynamics are essential for controlling bovine trypanosomiasis and mitigating its impact on the livestock industry in Nigeria.
Co-Authors Chukwuma Stephen Ezeonu David Christopher Bando Munirah Ibrahim Foku Omachonu Alkali Odoma Sarah Baba Gurama Silas Verwiyeh Tatah Usman Kesunga Yakubu Vera Akwa Yafeh Wama Binga Emmanuel