Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh
Mumya Camary
Departement of Anesthesiology and Intensive Therapy Arun Hospital
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Effects of Sedation Depth on Mechanical Ventilation, Delirium, and Recovery: A Systematic Review Anna Millizia; Mumya Camary; Muhammad Bayu Rizaldy; Yuziani
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 12 No.1 Mei 2026
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sedation is an essential component of intensive care unit (ICU) management; however, excessive sedation may adversely affect clinical outcomes. This systematic review evaluated the association between sedation depth and clinical outcomes in adult ICU patients receiving mechanical ventilation. A literature search was conducted according to PRISMA 2020 guidelines using PubMed, Scopus, Web of Science, and Google Scholar. Studies published between 2010 and 2023 assessing sedation depth with validated instruments in mechanically ventilated adults were included. Twelve studies involving more than 7,000 patients met the inclusion criteria. Most studies reported that deep sedation, particularly during the first 48 hours of ICU admission, was associated with higher mortality, prolonged mechanical ventilation, increased delirium incidence, and poorer long-term cognitive and functional outcomes. In contrast, light sedation strategies combined with regular assessment, sedation interruption, and multimodal analgesia were associated with reduced delirium risk, shorter ventilation duration, and improved recovery. Current evidence suggests that sedation depth significantly influences outcomes in critically ill patients. Light sedation should be considered whenever clinically appropriate, while further studies are needed to evaluate long-term recovery and develop individualized sedation approaches.
Co-Authors Anna Millizia Muhammad Bayu Rizaldy Yuziani