Benny
Staff of Department of Orthopaedics & Traumatology, Fakultas Kedokteran, Universitas Sumatera Utara/Adam Malik General Hospital, Medan

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Duration of Preoperative Anti-Tuberculosis Treatment (OAT) and Clinical Outcomes Post-Surgery in Spinal TB Patients: A Systematic Review and Meta-Analysis Gusnur Gazali Ashari; Benny; Iman Dwi Winanto
International Journal of Health, Economics, and Social Sciences (IJHESS) (Special Issue) - International Journal of Health, Economics, and Social Sciences (IJHESS)
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v7i2.7352

Abstract

Spinal tuberculosis (TB) is a rare but severe infection that can lead to deformities, back pain, and neurological deficits. Preoperative administration of anti-tuberculosis drugs (OAT) is commonly used to reduce bacterial activity and inflammation before surgery. However, the optimal duration of OAT preoperatively is still debated. This study aims to systematically review and analyze the relationship between preoperative OAT duration and clinical outcomes post-surgery in patients with spinal TB. A systematic review and meta-analysis were performed on studies comparing the effects of different OAT durations preoperatively in spinal TB patients. Data were collected from PubMed, Scopus, and EMBASE. Key outcomes evaluated included Visual Analog Scale (VAS) for pain, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), wound healing, and bone fusion.The meta-analysis showed that preoperative OAT duration of 1 to 2 weeks significantly reduced inflammation, with a notable decrease in ESR and CRP post-surgery (p = 0.006 for ESR, p = 0.02 for CRP). However, no significant differences in functional recovery or wound healing were observed between shorter (1-2 weeks) and longer (2-4 weeks) OAT durations. Bone fusion results were similar across both groups. A shorter duration of OAT preoperatively (1-2 weeks) is effective in reducing inflammation and improving postoperative recovery, though it does not significantly impact bone healing or fusion. Thus, a shorter preoperative OAT regimen can be considered a viable option in managing spinal TB patients.
A Systematic Review and Meta-Analysis of Healing Outcomes in Pediatric Lateral Humerus Condyle Fractures Treated with K-Wire Pin Fixation Tom Lieven Stefan Kurniawan; Benny; Heru Rahmadhany
International Journal of Health, Economics, and Social Sciences (IJHESS) (Special Issue) - International Journal of Health, Economics, and Social Sciences (IJHESS)
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v7i2.7406

Abstract

Sagittal balance refers to the equilibrium between external forces acting on the spine, particularly gravity, and the body's response to maintain an upright position with minimal muscular energy expenditure. Disruption of this balance can lead to sagittal imbalance, which is linked to poor clinical outcomes in conditions such as adult scoliosis and degenerative spondylolisthesis. The sedentary lifestyle, especially in office workers who spend significant time sitting, makes understanding spinal alignment changes in various positions crucial. This study aims to assess the differences in lumbopelvic sagittal balance in standing, upright sitting, and relaxed sitting positions in a healthy population. This analytical study used a case series approach with 25 healthy subjects aged 18-40. X-ray images were taken in three positions: standing, upright sitting, and relaxed sitting. Parameters including lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT), pelvic incidence (PI), and PI-LL mismatch were measured using RadiAnt DICOM Viewer. Data were analyzed using ANOVA to compare the sagittal balance parameters across different positions. differences were found in LL, SS, PT, and PI-LL mismatch between positions (p < 0.05). LL was highest in standing and lowest in relaxed sitting. PT increased significantly in relaxed sitting, while SS was highest in standing. PI did not show significant changes across positions. Lumbopelvic sagittal balance varies significantly between standing and sitting positions, highlighting the need to consider sitting postures in spinal assessments. These findings provide valuable insights for spine surgery planning and postural assessments.