Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Indonesian Journal of Chemical Science and Technology
Murniaty Simorangkir
State University of Medan
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Antibacterial Activity of Ethanol Extract of Nettle Leaves against Cutibacterium acnes and Pseudomonas aeruginosa Zuhairiah Nasution; Fira Yunita; Murniaty Simorangkir; Saronom Silaban; Nora Susanti
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75052

Abstract

Acne vulgaris is a common skin disorder associated with the growth of Cutibacterium acnes and Pseudomonas aeruginosa. This study aimed to evaluate the antibacterial activity of ethanol extract of nettle leaves (Urtica dioica) against both bacteria. The extract was obtained by maceration using 96% ethanol and subjected to phytochemical screening. Antibacterial activity was tested using the disc diffusion method at concentrations of 200, 400, and 800 mg/mL. The findings demonstrated that the extract contained alkaloids, phenolics, flavonoids, steroids, and saponins. The inhibition zones against Cutibacterium acnes were 14.17±0.21 mm, 16.03±0.76 mm, and 17.37±1.33 mm, while against Pseudomonas aeruginosa they were 9.63±0.51 mm, 12.23±0.40 mm, and 14.33±0.47 mm, respectively. Statistical analysis showed significant differences among treatments (p<0.05). These findings indicated that Urtica dioica leaf extract may serve as a potential natural antibacterial agent against acne-associated bacteria.
Green Synthesis and Antibacterial Activity of Silver Nanoparticles Using Ethanolic Extract from Clerodendrum fragrans Leaves Murniaty Simorangkir; Indah Sitanggang; Floren Miani Sihotang; David Septian Sibarani
Indonesian Journal of Chemical Science and Technology (IJCST) Vol. 9 No. 2 (2026): JULY 2026
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/ijcst.v9i2.75700

Abstract

Green synthesized silver nanoparticles using plant extract (AgNPs) have emerged as promising biomaterials for biomedical applications, particularly as antimicrobial agents. This study aimed to synthesize AgNPs using ethanolic leaf extract of sarang banua (Clerodendrum fragrans) and to evaluate their physicochemical characteristics and antibacterial activity for skin-related applications. C. fragrans leaf contains secondary metabolite bioactive compounds that can be involved in nanoparticle synthesis. In this approach plant-derived phytochemicals functioned as reducing and stabilizing agents. Antibacterial activity was tested using the disc diffusion method followed by determining the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The results of the study showed an average diameter of 114 nm with a polydispersity index (PDI) of 0.5, indicating moderate uniformity.The AgNPs showed strong inhibitory activity against Staphylococcus aureus as a representative skin-associated pathogenic bacteria with an inhibition zone of 11.06 mm. The minimum inhibitory concentration value was 3.375 µg/mL, while the minimum bactericidal concentration value exceeded 27 µg/mL, indicating bactericidal effects at higher concentrations. These findings highlight the potential of C. fragrans-mediated AgNPs as biomaterials for skin-related biomedical applications.
Co-Authors David Septian Sibarani Fira Yunita Floren Miani Sihotang Indah Sitanggang Nora Susanti Saronom Silaban Zuhairiah Nasution