<![CDATA[Background: Diabetes-related wounds are challenging to manage because impaired tissue repair, necrotic tissue, infection risk, and poor metabolic control may delay wound healing. Hydrogel dressings can support autolytic debridement by maintaining a moist wound environment, while antimicrobial dressings may be used as adjuncts when microbial burden is clinically relevant. Clinical documentation of serial wound changes during their combined use remains limited. This case series aimed to describe serial wound changes during hydrogel-assisted autolytic debridement combined with antimicrobial dressings in patients with diabetes-related wounds. Case Presentation: Three women with type 2 diabetes mellitus and necrotic or devitalized wounds were treated at an independent wound care clinic in Pekanbaru, Indonesia. Wound status was assessed using the Bates-jensen wound assessment tool (BJWAT) and serial photographs at baseline and on days 4, 8, and 12. Hydrogel-assisted autolytic debridement combined with antimicrobial dressings was applied as part of local wound management. BJWAT scores decreased from 28 to 18 in Case 1, from 20 to 10 in Case 2, and from 33 to 27 in Case 3. Serial wound assessments showed changes in wound appearance over the 12-day observation period, with varying degrees of improvement across the three cases. Conclusion: Decreases in BJWAT scores and improvements in wound appearance were observed across the three cases during the 12-day wound-care period. These findings provide descriptive clinical observations of wound progression during hydrogel-assisted autolytic debridement combined with antimicrobial dressings but do not establish the effectiveness of this treatment approach. Further controlled studies with longer follow-up and standardized assessment of wound characteristics and relevant patient-related factors are needed.]]>
