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All Journal Jurnal Biologi Tropis
Novianti Anggie Lestari
Fakultas Kedokteran Universitas Islam AL-Azhar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Correlation between HbA1c and TG/HDL Ratio with eGFR in Type 2 Diabetes Mellitus Patients in Risa Sentra Medika Hospital Mataram Novianti Anggie Lestari; Ima Arum Lestarini; Yan Adhitya Kusuma
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): Juli - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12284

Abstract

One of the main causes of declining kidney function is type 2 diabetes mellitus (DM2), which is typified by a drop in the estimated glomerular filtration rate (eGFR). The triglyceride-to-HDL (TG/HDL) ratio indicates atherogenic dyslipidemia, which contributes to the development of diabetic nephropathy, whereas HbA1c represents long-term glycemic management. This study aimed to analyze the correlation between HbA1c and TG/HDL ratio with eGFR in DM2 patients in Mataram. A cross-sectional analytical study was conducted involving 56 patients at Risa Sentra Medika Hospital from Juli to Desember 2025. Laboratory data were used to gather information on HbA1c, triglycerides, HDL, serum creatinine, and eGFR. The correlation between the variables was evaluated using regression analysis and Pearson correlation. The eGFR was 78.37 ml/min/1.73 m², the TG/HDL ratio was 5.84, and the mean HbA1c was 9.21%. The TG/HDL ratio had a very weak positive connection with eGFR (r = 0.143), but HbA1c had a very poor negative correlation (r = -0.037). According to regression analysis, neither variable was statistically significant (p>0.05) and only explained 2.2% of the variation in eGFR (R2 = 0.022). among conclusion, among patients with DM2, there was no discernible relationship between HbA1c and the TG/HDL ratio with eGFR.
Co-Authors Ima Arum Lestarini Yan Adhitya Kusuma