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All Journal Acta Pharmaciae Indonesia : Acta Pharm Indo
Ni Made Amelia Ratnata Dewi
Department of Pharmacy, Faculty of Medicine and Health Science, Universitas Mataram, Mataram 83125, West Nusa Tenggara, Indonesia
Medicine & Pharmacology

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Quality of life of hemodialysis patients with anemia in Lombok, Indonesia Candra Eka Puspitasari; Melda Putri Zakiah; Ni Luh Ayu Sri Widyasari; Ithnan Baqi Putra Erlangga; Kerthika Ayu Wandeni; Dinatul Aini; Sulthon Annaji; Widya Wulandari; Mahacita Andalusia; Yoga Dwi Saputra; Ni Made Amelia Ratnata Dewi
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 13 No 1 (2025): Acta Pharmaciae Indonesia: Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2025.13.1.15611

Abstract

Background: Anemia is a common complication of hemodialysis and is associated with substantial impairment of quality of life. Objective: This study evaluated the relationship between anemia biomarkers (hemoglobin and hematocrit) and health-related quality of life among patients receiving maintenance hemodialysis. Methods: A cross-sectional study was conducted at three hospitals on Lombok Island, Indonesia, involving 186 hemodialysis patients selected by purposive sampling. Quality of life was measured using the Indonesian-language KDQoL-SF36 questionnaire. Associations between hemoglobin, hematocrit, and quality-of-life scores were analyzed using Pearson's correlation and multiple linear regression (IBM SPSS version 29; p<0.05 considered significant). Results: The mean KDQoL-SF36 score was 63.60 ± 9.37. Age was significantly associated with quality of life (p = 0.024). Both hemoglobin and hematocrit showed significant positive correlations with quality of life (p<0.001), remaining significant predictors after multivariable adjustment. Conclusion: Hemoglobin and hematocrit levels are significant determinants of quality of life among hemodialysis patients. Optimizing anemia management, supported by active pharmacist involvement, may improve patient-reported outcomes in this population.
Co-Authors Candra Eka Puspitasari Dinatul Aini Ithnan Baqi Putra Erlangga Kerthika Ayu Wandeni Mahacita Andalusia Melda Putri Zakiah Ni Luh Ayu Sri Widyasari Sulthon Annaji Widya Wulandari Yoga Dwi Saputra