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All Journal Jurnal Kedokteran Diponegoro
Limdawati Kwee
Department of Internal Medicine, Faculty of Medicine, Maranatha Christian University, Indonesia
Medicine & Pharmacology

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PERICARDIAL EFFUSION DUE TO MYCOBACTERIUM TUBERCULOSIS AND STAPHYLOCOCCUS AUREUS COINFECTION IN IMMUNOCOMPETENT PATIENT: A CASE REPORT Limdawati Kwee; Aldrich Christiandy
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 15, No 5 (2026): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v15i5.53065

Abstract

Background: Pericardial effusion is a rare case, yet lethal if the treatment is not promptly given. Mycobacterium tuberculosis (MTB) is the leading cause of pericardial effusion in countries with high morbidity rate of tuberculosis, such as Indonesia. Generally, the infection happens in immunocompromised patients. Case presentation: This case report presented a 43-year-old female patient without comorbidities with worsening dyspnea exacerbated by dehydration due to acute diarrhea. The radiology imaging revealed the presence of cardiomegaly and pneumonia, meanwhile echocardiography revealed massive pericardial effusion. The pericardiocentesis result showed a negative Xpert TB result; however, elevated adenosine deaminase (ADA) and Staphylococcus aureus in the fluid culture were found. Antibiotic was given according to the culture sensitivity result as well as antituberculosis agents. Conclusion: From this case report, it is concluded that pericardial fluid culture is essential in improving diagnosis since coinfection can occur even to immunocompetent hosts. Immediate and appropriate management will reduce the fatal complication of cardiac tamponade.
Co-Authors Aldrich Christiandy