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All Journal International Journal of Health, Engineering and Technology
Elis Susilawati
Bhakti Kencana University, Bandung, West Java
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Vaccine Cold Chain Management in Primary Health Care Centers: Literature Review Yunistia Anggraini; Evi Junita Purnamasari; Elis Susilawati
International Journal of Health Engineering and Technology Vol. 5 No. 3 (2026): Vol. 5 No. 3 SEPTEMBER 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v5i3.1130

Abstract

Vaccine cold chain management is an essential component in ensuring vaccine quality, safety, and effectiveness until administration in immunization services. Primary health care centers play a strategic role in cold chain implementation; however, various studies report persistent challenges related to storage, temperature monitoring, distribution, and human resource capacity.  This article aims to comprehensively review vaccine cold chain management in primary health care centers by integrating national and international scientific evidence and pharmaceutical management perspectives. A narrative literature review was conducted using national and international databases, including articles published between 2020 and 2025 Of the 50 international and 25 national articles identified, screening based on titles, abstracts, and full-text assessment resulted in 14 relevant articles for analysis. The findings indicate that although most primary health care centers have implemented basic cold chain principles, significant gaps remain in temperature monitoring consistency, distribution documentation, utilization of supporting facilities, and pharmacist involvement in vaccine quality assurance systems. Strengthening the role of pharmacists, supported by temperature monitoring technology and adherence to national guidelines, is a key strategy to improve vaccine management quality in primary health care centers
Co-Authors Evi Junita Purnamasari Yunistia Anggraini