Nguyen Van Quoc
School of Chemistry, Biology and Environment, Vinh University, 182 Le Duan Street, Truong Vinh, Nghean 43000

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Recent Development in the Synthesis of 1,2,3-Triazole Derivatives Using Nanocatalysts Nguyen Van Quoc; Nguyen Thi Phuong Thao; Dau Xuan Duc
Bulletin of Chemical Reaction Engineering & Catalysis 2026: BCREC Volume 21 Issue 4 Year 2026 (December 2026) (Issue in Progress)
Publisher : Masyarakat Katalis Indonesia - Indonesian Catalyst Society (MKICS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9767/bcrec.20772

Abstract

1,2,3-Triazole is an aromatic, five-membered, π-excessive heterocycle comprised of three regular nitrogen atoms. 1,2,3-Triazoles possess a broad spectrum of bioactivities such as anticancer, antimicrobial, anti-inflammatory, antidiabetic, antiviral, and anti-HIV activity. Several compounds containing 1,2,3-triazole-moiety have been employed as drugs in the market. In organic synthesis, these heterocycles also play an important role as building blocks for different transformations. Furthermore, applications of 1,2,3-triazole derivatives as agrochemicals, corrosion retardants, polymers, optical brighteners, photostabilizers, pigments and metal chelators have also been well reported. Due to a wide range of applications, the synthesis of 1,2,3-triazoles has attracted tremendous research interest of chemists and a huge number of studies on the synthesis of these heterocycles have been published over the years. In this review article, we focus on the use of nanocatalysts for the synthesis of 1,2,3-triazoles. 70 studies on the synthesis of 1,2,3-triazoles using nanocatalyst from 2014 have been collected and analyzed. We also try to describe reaction mechanisms as much as we can. The study might be useful for chemists who work in heterocyclic synthesis or medicinal chemistry. Copyright © 2026 by Authors, Published by BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).