Medical oxygen is a critical component of hospital infrastructure, and its effective distribution is essentialfor maintaining continuity of patient care and safety. This study aimed to analyze medical gas distributionmanagement at Prof. Dr. H. Aloei Saboe Regional Hospital, Gorontalo, focusing on facilities and infrastructure,human resources, and the utilization of the Hospital Management Information System (SIMRS). A descriptivequalitative design was employed from August to October 2024. Data were collected through observation, in-depthinterviews, and documentation involving three informants consisting of the Head of the Hospital Facilities andInfrastructure Maintenance Unit (IPSRS), an IPSRS officer, and the Head of the Isolation Room. Data wereanalyzed through data organization, reduction, coding, categorization, cross-source comparison, and descriptiveinterpretation. The findings showed that oxygen distribution was supported by a centralized oxygen installation,reserve cylinders, routine external supply, and demand-based distribution. However, centralized and manualdistribution systems operated simultaneously, requiring direct stock monitoring and manual reporting. IPSRSstaffing was considered adequate for current operations, although afternoon and night shifts had fewer personneland staff had not received specific medical oxygen management training. SIMRS utilization was also limited,with oxygen monitoring, recording, and reporting at the IPSRS level remaining predominantly manual. The studyconcludes that medical oxygen distribution management is operationally functional but requires strengtheningthrough standardized procedures, competency-based training, improved contingency mechanisms, and greaterintegration of oxygen inventory and distribution monitoring into SIMRS to enhance efficiency, responsiveness,and patient safety.