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All Journal Majalah Obat Tradisional
Marini Damanik
Department of Chemistry, Universitas Negeri Medan, Medan, North Sumatra
Health Professions Medicine & Pharmacology Public Health

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Ethanol Extract of Frankincense: Study of Antifungal Potential Nora Susanti; Ruth Maria Meylisa Br Hutapea; Maria Aprina Br Surbakti; Muhammad Nizam; Marini Damanik
Majalah Obat Tradisional Vol 31, No 2 (2026)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.109042

Abstract

Natural products for phytopharmaca and cosmetics play a valuable role in the pharmaceutical industry. The sap of this plant contains secondary metabolic compounds, including alkaloids, flavonoids, and terpenoids, and has been proven to exhibit several biological activities such as antibacterial, antifungal, anti-inflammatory, and antimutagenic properties. Therefore, this research aimed to analyze the antifungal potential of the Indonesian indigenous frankincense (Styrax benzoin) extract before and after formulation as liquid soap. The result showed that both frankincense and the liquid soap formulations containing 2%, 4%, 6% and 8% extract exhibited strong growth inhibition against Candida albicans, Malassezia furfur, and Pityrosporum ovale using the disc paper method, comparable to the ketoconazole positive control. The lower frankincense concentration of 2% and 4% liquid soap maintained a stable appearance, acidity, and viscosity after storage.
Co-Authors Maria Aprina Br Surbakti Muhammad Nizam Nora Susanti Ruth Maria Meylisa Br Hutapea