<![CDATA[Introduction: Loss to follow-up cases among Human Immunodeficiency Virus (HIV) patients has clinical effects as well as impacts on the ARV therapy program. The risk of mortality is higher in HIV patients who experience loss to follow-up. This research aims to determine the basic profile and clinical profile of HIV patients who experienced loss to follow-up at the Referral Hospital in Surabaya. Methods: This research is a retrospective study, utilizing observations conducted through the analysis of patients' medical record data. The methodological approach employed in this study is the descriptive quantitative method. The number of HIV patients who experienced loss to follow-up at the Referral Hospital in Surabaya was 43 patients. 41 patients were included in the study sample inclusion criteria, and 2 patients were included in the exclusion criteria due to incomplete medical record data. Results: The study showed that the basic and clinical profile of HIV patients who experienced loss to follow-up at the Referral Hospital in Surabaya was as follows: male (63.41%), age range 20-39 years (36.59%), highest educational background SMA/SMK (53.66%), currently working (63.41%), normal BMI (41.46%), patients came alone to the HIV testing/counseling clinic (46,34%), risk factors were vaginal sex (50.00%), the combination of ART drugs consumed by the patient was the TDF+3TC+EVF regimen (39.02%), HIV clinical stage III (36.59%), CD4 values < 200 (29.27%), (80.49%) of the patients did not check their viral load, duration of loss to follow up < 4 years (26.83%), outcome was did not return to seek treatment (82,39%). Conclusion: This study describes HIV patients who experienced loss to follow-up at the Referral Hospital in Surabaya and emphasizes several key demographic and clinical traits that may inform future HIV care programs. The observed profile suggests that patients lost to follow-up frequently presented with advanced clinical status, insufficient virological monitoring, limited return to care, and other specific characteristics relevant to retention in HIV care. The results may serve as a basis for designing evidence-informed interventions to strengthen retention in HIV care and support sustained engagement in antiretroviral therapy.]]>
