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All Journal Media Ilmu Kesehatan
Cita Reast Wulansari
ABK PMI Jakarta
Health Professions Medicine & Pharmacology Nursing Public Health

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Changes in Hemoglobin Perubahan Kadar Hemoglobin dan Hematokrit Pada Pendonor Darah 450 ml dan 350 ml di UDD PMI Kabupaten Banyumas Tahun 2026 Reza Iqbal Suhada; Ria Syafitri EG; Srihartaty; Cita Reast Wulansari
MEDIA ILMU KESEHATAN Vol 15 No 2 (2026): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/mik.v15i2.2149

Abstract

Background: Blood donation is essential for maintaining the availability of blood and its components. Different blood bag volumes, 450 mL and 350 mL, may cause physiological changes, including alterations in hemoglobin and hematocrit levels.Objective: To determine changes in hemoglobin and hematocrit levels among donors using 450 mL and 350 mL blood bags at the Banyumas Regency Indonesian Red Cross Blood Donation Unit.Methods: This descriptive-analytic study used a pre-test and post-test design involving 60 donors, consisting of 30 donors using 450 mL bags and 30 using 350 mL bags. Samples were selected through accidental sampling. Data were analyzed using the independent t-test.Results: In the 450 mL group, mean hemoglobin decreased from 14.52 to 13.67 g/dL (p=0.000), while hematocrit decreased from 42.80% to 40.27% (p=0.000). In the 350 mL group, mean hemoglobin decreased from 13.98 to 13.86 g/dL (p=0.515), and hematocrit from 40.97% to 40.47% (p=0.395).Conclusion: Hemoglobin and hematocrit decreased after donation in both groups, with statistically significant changes observed only among donors using 450 mL blood bags
Co-Authors Ria Syafitri EG Srihartaty