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Ninny Meutia Pelupessy
Department of Pediatric, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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The Use of Azithromycin in Pediatric Typhoid Fever without Complication: A Case Report Emiral Amal; Ninny Meutia Pelupessy
Green Medical Journal Vol 6 No 1 (2024): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/gmj.v6i1.123

Abstract

Typhoid fever is an infection caused by the bacterium Salmonella typhi. The prevalence is still high among emerging countries, such as Indonesia. There are limited options for the treatment of typhoid fever in children and more so is complicated by the emergence of antimicrobial resistance. The use of azithromycin has evolved as an important drug in the treatment of typhoid. A male, aged 7 years and 2 months, was admitted to our hospital with remittent fever 4 days prior. The patient also presented with a period of cough since 2 days, and constipation, with full consciousness. The child had basic immunization completed for his age. He had a history of frequent consumption of street food. The diagnosis of typhoid fever was confirmed by serologic testing of positive 8 IgM Salmonella. Initially, the patient was treated with intravenous antibiotics of ceftriaxone for 8 days but shoed no clinical improvement, then the treatment was changed to intravenous azithromycin for 4 days and his condition improved greatly. The patient showed a better response with the use of azithromycin. The management of typhoid fever remains challenging up to this day with variations in treatment response. From this case, we can conclude that azithromycin in some patients may show better improvement in the management of typhoid fever in pediatric patients. Although, ceftriaxone and other third-generation cephalosporins are still highly effective against Salmonella typhi.
Biliary Atresia with Cytomegalovirus Infection, Congenital Heart Disease and Pneumonia: A Case Report Gracia Dewi; Setia Budi Salekede; Sri Hardiyanti Putri; Ninny Meutia Pelupessy; Mokhammad Ikhsan; Amiruddin Laompo
Green Medical Journal Vol 6 No 1 (2024): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/gmj.v6i1.137

Abstract

Biliary atresia (BA) is a condition of biliary obstruction. Kasai portoenterostomy (KPE) is a treatment option. The aim to determine the success rate of kasai procedure and prognosis in BA patients with other underlying diseases. This is a descriptive case study research. We report a boy, 2 months and 11 days with jaundice all over his body since one week old; putty stool, and dark urine. Old man's face, icteric, rib xylophone, subcostal retraction, rales, continuous heart murmur, and wasting. Total and direct bilirubin, SGOT, SGPT, and gamma GT are increased. A Kasai surgical procedure was carried out, but did not significantly improve his condition because the operation was performed at the age of 4 months and 8 days with liver cirrhosis, sepsis, pneumonia, and malnutrition. Cytomegalovirus (CMV) infection and acyanotic congenital heart disease also worsened his preoperative condition. Kasai portoenterostomy is a method of managing biliary atresia, but our patient was diagnosed with biliary atresia accompanied by CMV infection, congenital heart disease, or pneumonia, so the procedures not enough for this condition, and mortality rate is higher than biliary atresia alone. Age at surgery time also influences the prognosis.
Co-Authors Amiruddin Laompo Emiral Amal Gracia Dewi Mokhammad Ikhsan Setia Budi Salekede Sri Hardiyanti Putri