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All Journal Green Medical Journal
M Abrar Ismail
Department of Ophthalmology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Correlation of Myopia Degree with Central Corneal Thickness and Corneal Endothelial Density M Abrar Ismail; Wanty Burhanuddin; S Rukiah Syawal; Shelly Salmah
Green Medical Journal Vol 7 No 1 (2025): Green Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/gmj.v7i1.197

Abstract

Introduction: The anterior segment characteristics that may contribute to myopia are central corneal thickness and corneal endothelial cell density. The purpose of this study is to ascertain whether corneal endothelial density and central corneal thickness are associated with the degree of myopia. Methods: This cross-sectional observational analytical study was conducted from October to November 2018 at the Hasanuddin University Hospital in Makassar, Indonesia. Levior myopia (< -3.00 D) 61 eyes, moderate myopia (-3.00 D - -6.00 D) 30 eyes, and gravior myopia (> 6.00 D) 11 eyes comprised the 102 eyes of 65 myopic patients who participated in the study. The Snellen chart projector and trial lens set are used to test the refractive state of myopia. In contrast, the Nidek-CEM 530 specular microscope is used to measure the central corneal thickness and corneal endothelial cell density. Results: The high myopia group had the lowest CCT mean (521.3um; p: 0.199). The group with high myopia had the lowest mean ECD, 2777.6 (p<0.05). In cases of moderate myopia, a correlation between corneal ECD and CCT was found (p<0.05). Conclusion: The degrees of myopia and the CCT do not correlate. Reductions in corneal ECD are associated with myopia gravior. In moderate myopia, there is a strong positive relationship between corneal endothelial cell density and central corneal thickness.
Co-Authors S Rukiah Syawal Shelly Salmah Wanty Burhanuddin