Nutritional problems among children under five remain a public health challenge in Indonesia, including in Klungkung Regency, Bali. Acupressure is a complementary therapy that may help improve appetite in children under five with nutritional problems through stimulation of specific meridian points. This study aimed to evaluate changes in anthropometric indicators and appetite before and after an acupressure intervention among children under five with nutritional problems at Klungkung II Public Health Center. A quantitative approach with a pre-experimental one-group pretest–posttest design was employed, involving 32 children under five with nutritional problems selected through purposive sampling. The acupressure intervention was administered at five points—ST36 (Zusanli), CV12 (Zhongwan), SP3 (Taibai), SP6 (Sanyinjiao), and ST25 (Tianshu)—in three sessions lasting 10–15 minutes each over a three-week period. Body weight and height were analyzed using paired-samples t-tests, whereas z-scores and appetite scores were analyzed using the Wilcoxon signed-rank test. The results showed that mean body weight increased from 10.94 kg to 11.52 kg and mean height from 89.53 cm to 90.35 cm after the intervention. The mean weight-for-age z-score increased from −2.36 to −1.74, while the mean height-for-age z-score increased from −2.02 to −1.69. Appetite scores also increased from 24.68 to 33.15. Differences between pre- and post-intervention measurements were statistically significant for all indicators (p < 0.001). These findings indicate differences between pre- and post-intervention conditions; however, the observed changes cannot be fully attributed to acupressure because the study did not include a control group.