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All Journal Biology, Medicine, & Natural Product Chemistry
Olapeju Oluyemisi Aiyelaagbe
Abiola Ajimobi Technical University
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

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Gomphrena nitida Rothr. (Amaranthaceae): Phytochemical Evaluation and Antioxidant Activities of Roots, Stem, and Leaves Ayopo Anuoluwa Sotade; Olayombo Margaret Banwo; Olapeju Oluyemisi Aiyelaagbe
Biology, Medicine, & Natural Product Chemistry Vol 15, No 2 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.152.1873-1882

Abstract

Gomphrena nitida Rothr. (Amaranthaceae) is traditionally used to manage oxidative stress-related ailments, infections, and inflammation. This study evaluated the phytochemical composition and antioxidant potential of root, stem, and leaf extracts obtained using hexane, ethyl acetate, and methanol. Qualitative and quantitative analyses revealed flavonoids, glycosides, steroids, and terpenoids across all extracts, with methanol and ethyl acetate fractions showing richer profiles. The highest flavonoid (36.89 mg/g quercetin equivalent) and phenolic (18.59 mg/g gallic acid equivalent) contents were found in leaf and root extracts, respectively. Root methanol extract showed the strongest DPPH activity (IC50 = 168.12 µg/mL), comparable to ascorbic acid (IC50 = 136.97 µg/mL), while root hexane extract exhibited the highest FRAP value (582.14 mg AAE/g). The strong antioxidant potential correlates with high phenolic and flavonoid contents, supporting the traditional use of G. nitida and highlighting its promise as a source of natural antioxidants for managing oxidative stress-related conditions.
Co-Authors Ayopo Anuoluwa Sotade Olayombo Margaret Banwo