<![CDATA[Introduction: Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis common in elderly and hypertensive patients. Anatomical lesion complexity is assessed using the Global Limb Anatomic Staging System (GLASS), yet its association with age and hypertension duration remains understudied, particularly in Indonesia. This study aimed to assess the association of age and duration of hypertension with vascular anatomical complexity based on the GLASS classification in hypertensive PAD patients. Methods: This cross-sectional analytical observational study used medical record data from hypertensive PAD patients who underwent computed tomography angiography (CTA). Bivariate analysis used the One-Way ANOVA and Kruskal-Wallis tests, while multivariate analysis used ordinal logistic regression. Results: A total of 97 patients met the inclusion and exclusion criteria. The mean age was 64.65 ± 11.17 years, and the median duration of hypertension was 5 years (range: 1–35 years). GLASS stage distribution was dominated by stage III (43.3%), followed by stage II (41.2%) and stage I (14.4%). Age was not significantly associated with GLASS stage in bivariate analysis (p = 0.776), whereas duration of hypertension was (p = 0.044). In multivariate analysis, neither age nor duration of hypertension was significantly associated with GLASS stage (p > 0.05). Anatomical complexity in PAD cannot be predicted from age or hypertension duration alone, so revascularization still requires comprehensive GLASS evaluation. Conclusion: Age was not associated with lesion complexity as defined by GLASS, while hypertension duration showed a significant bivariate association not confirmed on multivariate analysis.]]>
