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All Journal Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Pratiwi Nasir Hamzah
Fakultas Kedokteran, Universitas Muslim Indonesia, Rumah Sakit "IBNU SINA" YW-UMI, Makassar, Sulawesi Selatan, 90231, Indonesia
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Association Between Glycemic Control Parameters (HbA1c and Random Blood Glucose) And Pulmonary Tuberculosis Status Among Patients With Type 2 Diabetes Mellitus Preity Nefythalia Ikhrimatunnisya; Andi Kartini Eka Yanti; Fardeana Tri Chandra Armon; Indah Lestari Daeng Kanang; Pratiwi Nasir Hamzah
Syifa'Medika Vol 17, No 1 (2026): Syifa Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v17i1.10971

Abstract

ABSTRACTType 2 diabetes mellitus (T2DM) is a condition that may increase susceptibility to pulmonary tuberculosis (TB) through impaired immune function associated with hyperglycemia. This study aimed to analyze the association of hemoglobin A1c (HbA1c) and random blood glucose (RBG) levels with pulmonary TB status among patients with T2DM at Ibnu Sina Hospital Makassar in 2024. This cross-sectional study used secondary data obtained from medical records. A total of 165 patients with T2DM were selected using purposive sampling. Data were analyzed using univariate and bivariate analyses with the Chi-square test or Fisher’s Exact Test according to the characteristics of the data. Among the 165 patients, 20 (12.1%) had pulmonary TB. The proportion of pulmonary TB was 10.7% among patients with controlled HbA1c and 12.4% among those with uncontrolled HbA1c. There was no significant association between HbA1c and pulmonary TB status (p=1.000; POR=1.181). The proportion of pulmonary TB was 11% among patients with normal RBG and 13% among those with elevated RBG, with no significant association between RBG and pulmonary TB status (p=0.867; POR=1.219). In conclusion, HbA1c and RBG were not significantly associated with pulmonary TB status among patients with T2DM in this study. Further studies with larger sample sizes and adjustment for potential confounding factors are needed to provide a more comprehensive understanding of the relationship between glycemic control and pulmonary TB
Association Between Serum Uric Acid Level and Clinical Characteristics and the Degree Of Knee Osteoarthritis Andi Natasya Dewanti Idris; Abdul Mubdi Ardiansar Karim Arifuddin; Susdiaman Susdiaman; Fadil Mula Putra; Pratiwi Nasir Hamzah
Syifa'Medika Vol 17, No 1 (2026): Syifa Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v17i1.10997

Abstract

Genu osteoarthritis (OAG) is a degenerative joint disease influenced by mechanical and metabolic factors. Uric acid levels may be associated with inflammatory and metabolic processes accompanying OAG; however, the relationship between uric acid levels and the clinical characteristics and severity of OAG remains inconsistent. This study aimed to analyze the association of uric acid levels with age, sex, body mass index (BMI), and OAG severity based on the Kellgren-Lawrence classification among patients with OAG at Ibnu Sina Hospital Makassar in 2026. This analytical observational study used a cross-sectional design and included 41 patients with OAG. Uric acid levels were measured from capillary blood using a GCU meter, while BMI was obtained from anthropometric measurements and OAG severity was determined from medical records based on the Kellgren-Lawrence classification. Bivariate analysis was performed using the Chi-Square test. Hyperuricemia was identified in 21 patients (51.2%), while 24 patients (58.5%) had Grade 3–4 OAG. A significant association was found between BMI and uric acid levels (p=0.014), with all patients classified as obesity class II having hyperuricemia. No statistically significant association was found between uric acid levels and age (p=0.342), sex (p=0.277), or OAG severity (p=0.208). In this study, uric acid levels were associated with BMI but were not statistically associated with age, sex, or OAG severity. These findings should be interpreted in consideration of the limited sample size and cross-sectional design.
Co-Authors Abdul Mubdi Ardiansar Karim Arifuddin Andi Kartini Eka Yanti Andi Natasya Dewanti Idris Fadil Mula Putra Fardeana Tri Chandra Armon Indah Lestari Daeng Kanang Preity Nefythalia Ikhrimatunnisya Susdiaman Susdiaman