Poor household waste management is one of the major determinants of the high incidence of environmentally related diseases, particularly diarrhea. This community service activity aimed to educate the community, identify the relationship between waste disposal practices and the incidence of diarrhea, and improve the health status of residents in Dasan Agung Village, Mataram City. The community service program employed a Community-Based Participatory Research (CBPR) approach, consisting of environmental sanitation awareness activities, household-level waste segregation training, community-based environmental clean-up activities, and an observational survey involving 80 heads of households. Data were collected through questionnaires assessing household waste management practices and the history of diarrhea episodes during the previous three months, and were subsequently analyzed using the Chi-Square correlation test. The results demonstrated a 38% increase in community knowledge regarding the impact of improper waste disposal on the proliferation of disease vectors, such as flies. Based on the survey data analysis, a significant association was found between open/improper waste disposal practices and an increased frequency of diarrhea among residents (p-value < 0.05). Residents who managed waste properly and kept waste containers tightly covered experienced a significant reduction in diarrhea cases. This activity successfully encouraged the establishment of a community-based self-managed waste bank and the provision of segregated waste bins in residential areas of Dasan Agung. In conclusion, educational interventions and assistance in waste management were effective in promoting behavioral changes among community members and reducing the risk of diarrhea transmission. It is recommended that the sanitation monitoring program be sustained through regular supervision by local health cadres.