<![CDATA[Background: Acne vulgaris is a common skin disorder, particularly among adolescents and young adults in Indonesia. Conventional acne therapies, including antibiotics and synthetic topical agents, may cause adverse effects and bacterial resistance. Therefore, natural alternatives are needed. Decaffeinated Arabica coffee (Coffea arabica L.) extract contains bioactive compounds, particularly chlorogenic acid, with antibacterial and anti-inflammatory activities, showing potential for acne-prone skin care. Objective: This study aimed to formulate and evaluate the physical characteristics of an acne patch containing decaffeinated Arabica coffee bean extract. Methods: This experimental study employed a descriptive approach. Arabica coffee beans from Cigalontang, Tasikmalaya Regency, Indonesia, were decaffeinated through pineapple juice fermentation for 60 hours and extracted using Soxhlet extraction with 70% ethanol. The extract was evaluated for yield and phytochemical constituents before formulation into an HPMC-based acne patch. Characterization included organoleptic evaluation, pH, weight, thickness, and folding endurance. Data were analyzed descriptively and presented as mean ± standard deviation. Results: The extract yield was 9.48%. Phytochemical screening revealed alkaloids, flavonoids, saponins, polyphenols, tannins, and triterpenoids, while steroids were absent. The acne patch exhibited a heart-shaped appearance, yellowish-brown color, characteristic coffee aroma, and a smooth, uniform, adhesive surface. The pH, weight, and thickness were 4.76 ± 0.13, 0.0389 ± 0.0047 g, and 0.06 ± 0.02 mm, respectively, with folding endurance exceeding 300 folds. Conclusion: Decaffeinated Arabica coffee bean extract was successfully formulated into an acne patch with satisfactory physical characteristics based on the evaluated parameters. Further studies are needed to evaluate biological activity, efficacy, stability, and dermal safety.]]>
