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All Journal KOLONI
Nur Salsabila Sandy
Rumah Sakit Umum Pusat Surabaya
Civil Engineering, Building, Construction & Architecture Law, Crime, Criminology & Criminal Justice Public Health Social Sciences Other

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Peranan Sekuen Arterial Spin Labelling (ASL) pada pemeriksaan MRI Brain Perfusi dengan Kasus Stroke Iskemik di RSUP Surabaya Ni Kadek Paramita Putri Arta; Langkir Sapto Adi; Nur Salsabila Sandy
KOLONI Vol. 5 No. 3 (2026): SEPTEMBER 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i3.1388

Abstract

Ischemic stroke is a disorder of cerebral blood flow that can cause brain tissue damage, thus requiring imaging examinations capable of providing structural and perfusion information. Magnetic Resonance Imaging (MRI) can evaluate tissue changes through various sequences, while Arterial Spin Labeling (ASL) provides information on cerebral perfusion without the use of exogenous contrast agents. This study aims to analyze the brain MRI examination procedure in cases of ischemic stroke and to identify the role of ASL sequences in providing information on cerebral blood flow (CBF). The study employed a qualitative descriptive design, with MRI radiographers who were directly involved in brain MRI examinations of patients with ischemic stroke serving as informants. Data were collected through interviews and analyzed through data organization, reduction, categorization based on themes, descriptive presentation, and drawing of conclusions. The results showed that brain MRI examinations include patient preparation, positioning, and the acquisition of several MRI sequences, namely DWI, T2 FLAIR, T2-weighted, T1-weighted, MRA, and ASL. The type of ASL used is pseudo-continuous arterial spin labeling (pCASL). The pCASL sequence is used to assess CBF and provides cerebral perfusion information that complements the anatomical, diffusion, and vascular information from other MRI sequences without the use of contrast media.
Peranan T1-Weighted Post-Contrast dan Dynamic Susceptibility Contrast (DSC) Perfusion pada Pemeriksaan MRI Brain Pasien dengan Indikasi Klinis Epilepsi di Rumah Sakit Umum Pusat Surabaya Putu Amanda Prasaka Putri; Ni Putu Rita Jeniyanthi; Nur Salsabila Sandy
KOLONI Vol. 5 No. 3 (2026): SEPTEMBER 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i3.1402

Abstract

Epilepsy is a neurological disorder characterized by recurrent seizures caused by abnormal electrical activity in the brain and may be associated with structural or functional abnormalities. Magnetic resonance imaging (MRI) plays an important role in identifying the underlying causes of epilepsy and determining the need for additional imaging techniques. This study aimed to describe the role of T1-weighted post-contrast and Dynamic Susceptibility Contrast (DSC) perfusion in brain MRI examinations of patients with clinical indications of epilepsy at RSUP Surabaya. This study used a qualitative descriptive method with a multiple case study design involving three patients who underwent brain MRI examinations using a 1.5 Tesla Philips MRI scanner. Data were collected through image observation, examination documentation, radiology reports, and interviews with two radiographers and one radiologist. The results showed that T1-weighted post-contrast contributed to the evaluation of enhancement characteristics, particularly in a patient with a right temporal mass showing strong enhancement. In suspected mesial temporal sclerosis, the main findings were obtained from structural sequences, showing bilateral hippocampal FLAIR hyperintensity with right hippocampal atrophy without abnormal enhancement. DSC perfusion provided additional information regarding tissue perfusion, showing perfusion differences between the lesion and contralateral tissue in the mass case. This study concludes that T1-weighted post-contrast and DSC perfusion have complementary roles and can be selectively applied according to MRI findings and clinical needs in epilepsy patients.
Co-Authors Langkir Sapto Adi Ni Kadek Paramita Putri Arta Ni Putu Rita Jeniyanthi Putu Amanda Prasaka Putri