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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Made Krisna Adi Jaya
Department of Pharmacy, Faculty of Math and Science, Universitas Udayana, Bali
Health Professions Medicine & Pharmacology Public Health

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Body Mass Index Profiles by Antidiabetic Regimen Complexity Among Hospital-Based Patients with Type 2 Diabetes Mellitus in Indonesia Made Krisna Adi Jaya; Putu Rika Veryanti; Baiq Leny Nopitasari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.119644

Abstract

Background: Excess body weight is common in type 2 diabetes mellitus (T2DM) and may influence treatment selection, but BMI profiles by antidiabetic regimen complexity remain underexplored in Indonesian hospital settings.Objectives: This study aimed to describe BMI profiles across antidiabetic regimen complexity among patients with T2DM in Indonesia.Methods: This multicenter cross-sectional study used secondary hospital-based data from 628 adult patients with T2DM from three Indonesian study sites in Jakarta, Bali, and Mataram. Patients were identified using ICD-10 codes E11.0-E11.9. BMI was categorized using Asian cut-off points, and antidiabetic regimens were classified according to the number of documented drug classes. Descriptive analyses summarized BMI and regimen patterns. One-way ANOVA compared mean BMI across regimen complexity groups, while chi-square and linear-by-linear association tests examined obesity grade distribution.Results: The mean age was 59.02 ± 11.34 years, and mean BMI was 25.72 ± 4.20 kg/m². Overall, 352 patients (56.1%) were obese. Monotherapy was the most common regimen complexity group (57.5%), followed by dual therapy (30.4%), triple therapy (10.0%), and ≥4 drug classes (1.0%). Mean BMI differed significantly across regimen complexity groups (p=0.025), and obesity grade showed an ordinal trend across increasing numbers of documented antidiabetic drug classes (p=0.017).Conclusion: Obesity was common among patients with T2DM in this secondary hospital-based dataset. Given the cross-sectional design, the observed association between higher numbers of documented antidiabetic drug classes and less favorable BMI profiles should not be interpreted as causal or as reflecting disease severity or therapeutic intensity.
Co-Authors Baiq Leny Nopitasari Putu Rika Veryanti