The contemporary security environment in Nigeria and West Africa is increasingly characterized by complex, interconnected, and rapidly evolving threats, including terrorism, armed banditry, kidnapping, violent extremism, transnational organised crime, cybercrime, communal conflicts, separatist violence, trafficking, illicit arms proliferation, resource-based conflicts, political instability, and climate-related insecurity. These threats frequently develop through identifiable patterns before escalating into full-scale security crises. However, the effectiveness of national and regional security institutions is often constrained by fragmented intelligence systems, inadequate information sharing, weak analytical capacity, poor coordination among security agencies, limited technological infrastructure, insufficient community participation, and the persistent gap between early warning and early action. This study examines the role of intelligence-led early warning systems in strengthening national security and preventing emerging security threats in Nigeria and West Africa. It develops a strategic framework that integrates intelligence collection, data fusion, predictive analysis, community-based information, technological surveillance, inter-agency coordination, regional intelligence sharing, risk assessment, decision-making, and preventive response. The study adopts a qualitative documentary research design, relying on secondary sources including academic literature, official reports, policy documents, institutional publications, and regional security frameworks. The analysis is anchored principally in Intelligence-Led Policing Theory, Human Security Theory, and Systems Theory. The paper argues that early warning becomes strategically valuable only when intelligence is transformed into timely, credible, actionable information and connected to clearly defined response mechanisms. Existing regional arrangements such as the ECOWAS Warning and Response Network (ECOWARN) and the African Union Continental Early Warning System (CEWS) provide important foundations, but their effectiveness depends on stronger national-regional linkages, interoperable information systems, analytical capacity, trusted community networks, and political willingness to act on warnings. The study proposes an Intelligence-Led Early Warning and Preventive Security Framework (ILEW-PSF) for Nigeria and West Africa. It recommends the establishment of integrated national intelligence fusion mechanisms, real-time risk dashboards, predictive analytics capacity, community intelligence networks, stronger border intelligence, improved intelligence-sharing protocols, early-action triggers, professional training, legal safeguards, and closer cooperation among Nigeria, ECOWAS, the African Union, and other relevant stakeholders.