<![CDATA[Background: Exclusive breastfeeding (ASI) is an effective intervention in improving health status and reducing infant morbidity and mortality. However, the coverage of exclusive breastfeeding in Indonesia has not yet reached the established target. One factor suspected to play a role in the success of exclusive breastfeeding is mothers' knowledge of the benefits and practices of breastfeeding. Objective: This study aims to analyze the relationship between mothers' knowledge about exclusive breastfeeding and the success of exclusive breastfeeding at the Independent Midwife Practice Center (TPMB) in Bandung Regency. Methods: This study used an observational analytical design with a cross-sectional approach. The study sample consisted of 42 breastfeeding mothers with infants aged 6–12 months and was selected using a total sampling technique. Data were collected using a structured questionnaire regarding mothers' knowledge about exclusive breastfeeding and their history of exclusive breastfeeding. Data were analyzed univariately to describe respondent characteristics and the distribution of study variables, and bivariate analysis using the Chi-Square test with a significance level of α = 0.05. Results: The study showed that 20 respondents (47.6%) had good knowledge, 15 respondents (35.7%) had sufficient knowledge, and 7 respondents (16.7%) had insufficient knowledge. Twenty-seven respondents (64.3%) were successful in providing exclusive breastfeeding, while 15 respondents (35.7%) were unsuccessful. Chi-square test results showed a significant relationship between maternal knowledge about exclusive breastfeeding and successful exclusive breastfeeding (p = 0.001). Mothers with good knowledge had a higher proportion of successful exclusive breastfeeding (90.0%) compared to mothers with sufficient knowledge (53.3%) and those with insufficient knowledge (14.3%). Conclusion: There is a significant relationship between maternal knowledge about exclusive breastfeeding and successful exclusive breastfeeding in the TPMB (Family Welfare Center) in Bandung Regency. Improving maternal knowledge through continuous health education and lactation counseling from pregnancy to postpartum needs to be strengthened as a strategy to increase the success of exclusive breastfeeding and support the achievement of maternal and child health program targets.]]>
