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All Journal Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Vania Santika Putri
Politeknik Indonusa Surakarta, Indonesia
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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FORMULASI DAN EVALUASI FISIK SEDIAAN PASTA GIGI EKSTRAK DAUN BELUNTAS DENGAN VARIASI KONSENTRASI GLISERIN Khoilal Septia Al khoir; Vania Santika Putri; Riyan Setiyanto
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 8 No. 1 (2024): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v8i1.188

Abstract

Beluntas leaves (Pluchea indica) are a plant that has alkaloid, tannin and flavonoid compounds so it can be used as an antibacterial against streptococcus mutans which causes dental caries with an inhibitory power of 13.9 mm at a concentration of 5% (strong). Beluntas leaves can be developed into a toothpaste preparation. The aim of this research was to determine the formulation and physical evaluation of beluntas leaf extract toothpaste preparations with varying glycerin concentrations.Making beluntas leaf extract using the maceration method with 96% solvent ethanol ratio 1:10. Making toothpaste with varying glycerin concentrations, F1(5%), F2(7.5%), F3(10%). Physical evaluation of toothpaste preparations includes organoleptic, homogeneity, pH, high foam, spreadability and viscosity.Organoleptic tests of the three formula has a distinctive menthol odorhave the same odor, semi form solid and dark green color. The homogeneity test results F1= not homogeneous, F2= homogeneous, F3= homogeneous. Toothpaste pH test results F1 = 7.22 ± 0.10, F2 = 7.38 ± 0.12, F3 = 8.20 ± 0.35. The results of the toothpaste viscosity test were 9814.8 ± 0.55 cps, F2 = 9812.9 ± 0.59 cps, F3 =9811, 7±0.74 cps. The spreadability test results of toothpaste were F1=2.92±0.09 cm, F2=2.94±0.34 cm, F3=3.20±0.21 cm. Test results for toothpaste foam height F1 = 5.67 ± 0.67 mm, F2 = 5.67 ± 0.34 mm, F3 = 7.00 ± 0.33 mm. Based on the results of the One Way Anova test and the Kruskal Wallis test, it was concluded that variations in glycerin concentration had a significant effect on the spreadability, pH and viscosity tests.
TINGKAT PENGETAHUAN SWAMEDIKASI OBAT ANALGESIK PADA MASYARAKAT DUSUN NGLEMPONG, DESA SUKOREJO, KECAMATAN WONOSARI, KABUPATEN KLATEN Yunita Dian Permatasari; Vania Santika Putri; Giwang Unin Nugroho
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 8 No. 1 (2024): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v8i1.190

Abstract

Self-medication is an effort made by people to treat themselves without instructions from a doctor to treat conditions they recognize or diagnose themselves. Analgesics are one of the drugs that are widely used by the public for self-medication. The implementation of self-medication is related to the use of medication and the accuracy of dosage. This study aims to determine the level of knowledge of self-medication of analgesic drugs in the community of Nglempong Hamlet, Sukorejo Village, Wonosari District, Klaten Regency. This research is a type of non-experimental research that is descriptive in nature and uses a purposive sampling method for sampling with inclusion and exclusion criteria. The sample in this study was 86 respondents who were obtained through calculations using the Slovin formula. Collecting data distributes questionnaires then the data obtained is processed into a table to get a percentage. The results of the research regarding self-medication knowledge showed that 64% of respondents had a good level of knowledge, 29.0% of respondents had a medium level of knowledge and 7.0% of respondents had poor knowledge. Regarding analgesic self- medication, it can be concluded that the average respond ent's knowledge regarding analgesics is classified as good (80%).
FORMULASI DAN EVALUASI FISIK SEDIAAN KRIM EKSTRAK ETANOL BUNGA KAMBOJA PUTIH (Plumeria acuminata) DENGAN VARIASI KONSENTRASI TRIETANOLAMIN DAN ASAM STEARAT Novita Anggraini Nurhidayati; Vania Santika Putri; Dewi Weni Sari
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 8 No. 1 (2024): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v8i1.191

Abstract

Tanaman bunga kamboja putih (Plumeria acuminata) mempunyai aktivitas antioksidan tinggi dengan nilai IC50 sebesar 38,50 ppm. Bunga kamboja putih mengandung senyawa tanin, flavanoid, dan alkaloid. Salah satu sediaan yang dapat digunakan untuk mengatasi penuaan dini adalah krim. Penelitian ini bertujuan untuk mengetahui formulasi dan evaluasi fisik serta pengaruh variasi konsentrasi emulgator terhadap sifat fisik sediaan krim ekstrak bunga kamboja putih (Plumeria acuminata). Pembuatan ekstrak bunga kamboja putih menggunakan metode maserasi dengan pelarut etanol 70% dengan perbandingan 1:10. Krim dibuat dengan memvariasikan konsentrasi asam stearat dan trietanolamin F1 (16%:2%), F2 (15%:3%) dan F3 (14%:4%). Evaluasi fisik yang dilakukan meliputi uji organoleptis, homogenitas, pH, daya lekat, viskositas dispersi, jenis krim. Hasil uji organoleptik ketiga formula mempunyai warna, bau, tekstur yang sama. Hasil uji homogenitas menunjukkan ketiga formula homogen. Hasil uji pH krim F1=6,24±0,04, F2=6,49±0,01, F3=6,81±0,05, yang mana F3 belum memenuhi syarat. Hasil uji daya sebar krim F1=5,33±0,83 cm, F2=5,46±0,45 cm, F3=5,61±0,46 cm telah memenuhi syarat. Hasil uji daya lekat krim yaitu F1=5,1±3,47 (detik), F2=2,72±0,36 (detik), F3=2,31±1,12 (detik), ynag mana F2 dan F3 belum memenuhi syarat. Hasil uji viskositas krim F1=3913.1±0.36 cps, F2=3912.7±0.62 cps, F3=3912.2±1.25 cps telah memenuhi syarat. Variasi trietanolamin dan asam stearat mempengaruhi evaluasi fisik uji pH dan tidak berpengaruh pada uji dispersi, adhesi, dan viskositas.
Co-Authors Dewi Weni Sari Giwang Unin Nugroho Khoilal Septia Al khoir Novita Anggraini Nurhidayati Riyan Setiyanto Yunita Dian Permatasari