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All Journal Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
indah indah
Sriwijaya University
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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DETEKSI DAN KUANTIFIKASI LOGAM TEMBAGA (Cu) DALAM IKAN PATIN (Pangasianodon hypophthalmus) SUNGAI MUSI PALEMBANG MENGGUNAKAN METODE SPEKTROFOTOMETRI SERAPAN ATOM indah indah; Risa Astuti; Sarah Hanifah Az-Zahra Anwar
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.287

Abstract

Copper (Cu) is a toxic heavy metal that can accumulate in aquatic organisms, including edible fish. The Patin fish (Pangasianodon hypophthalmus) is an effective bioindicator for assessing heavy metal contamination in the Musi River, Palembang. This study determined Cu concentrations in Patin fish collected from three locations: Kuto Batu, 10 Ulu, and 5 Ulu, using Atomic Absorption Spectrophotometry (AAS). Cu levels were 0.60819 mg/kg (Kuto Batu), 1.08638 mg/kg (10 Ulu), and 1.01736 mg/kg (5 Ulu), all within the maximum limits for food safety. However, these results highlight the potential for Cu exposure in the Musi River ecosystem, which may pose cumulative risks to food safety and public health if concentrations increase over time.
PERBANDINGAN AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BIJI KOPI ARABIKA (Coffea arabica L.) DAN KOPI ROBUSTA (Coffea canephora L.) SEMENDE DARAT LAUT SUMATERA SELATAN Indah Indah; Wahyu Wahyu; Yovi Pranata
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 10 No. 1 (2026): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v10i1.329

Abstract

This research was conducted to determine and compare the antioxidant capacity of 70% ethanolic extracts of Arabica (Coffea arabica L.) and Robusta (Coffea canephora L.) coffee beans collected from Semende Darat Laut, South Sumatra, Indonesia. The coffee beans were extracted by maceration using 70% ethanol, while free-radical scavenging activity was examined by the DPPH (1,1-diphenyl-2-picrylhydrazyl) assay and read at 517 nm using UV-Vis spectrophotometry. The Arabica bean extract produced an IC₅₀ of 38.879 µg/mL and was classified as having very strong antioxidant activity. In comparison, the Robusta extract yielded an IC₅₀ of 52.402 µg/mL, which falls into the strong category. As the positive control, vitamin C showed an IC₅₀ of 29.636 µg/mL. Qualitative phytochemical tests detected phenolic compounds, saponins, and steroids in both extracts. These results suggest that Arabica coffee beans from Semende Darat Laut exhibit stronger antioxidant potential than Robusta beans, presumably due to differences in phenolic constituents, including chlorogenic acid. Thus, both local coffee varieties may be considered prospective natural antioxidant sources for health-related product development.
Co-Authors Risa Astuti Sarah Hanifah Az-Zahra Anwar Wahyu Wahyu Yovi Pranata