Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Media Gizi Indonesia (MGI)
Erni Sofia Murtini
Faculty of Agricultural Technology, Universitas Brawijaya, Malang 65145, East Java, Indonesia
Health Professions

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Sub-Acute Effects of Durian and Beta-Glucan on Cardiovascular Risk Markers and Gut Hormones in Male Rats Abbe Maleyki Mhd Jalil; Atirah A Aziz; Napisah Hussin; Anuar Md Zain; Muhammad Ibrahim; Erni Sofia Murtini; Nurul Huda
Media Gizi Indonesia Vol. 21 No. 4 (2026): MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v21i4.633-644

Abstract

Durian (Durio zibethinus Murr.) consumption increased postprandial glycemic and lipid profiles. This study determine the effect of adding soluble beta-glucan with durian on posptprandial glycemic, lipid profiles and gut hormones (peptide YY, glucagon-like peptide-1, cholecystokinin). Rats were divided to Positive Control, Durian, Beta-Glucan, Durian + Beta-Glucan and Negative Control (normal diet). Durian (114.5 g) and 4 g of beta-glucan were converted to animal equivalent dose (AED). The formulations were given using an oral gavage. Blood was collected at the end of week 2. Durian + Beta-Glucan showed significantly (p<0.05) lower food intake compared with Beta-Glucan group.  Durian and/or Beta-glucan showed similar fasting glycemic, insulin, C-peptide and gut hormones compared with controls and baseline for all treatment groups. Rats fed with Durian + Beta-Glucan showed significantly (p<0.003) higher LDL-c compared with baseline with 0.42 (0.37-0.54) and 0.16 (0.08-0.26) mmol/L, respectively. This study suggests that a combination of durian and beta-glucan reduced food intake and has no negative effects on glycaemic response. The effects could be due to increase stomach distention or slower gastric emptying. It is imperative to note that sub-acute durian supplementation was associated with higher LDL-c but this needs to be confirmed in human study.
Co-Authors Abbe Maleyki Mhd Jalil Anuar Md Zain Atirah A Aziz Muhammad Ibrahim Napisah Hussin Nurul Huda